Results 121 to 130 of about 88,144 (310)

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

open access: yesAddiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden   +10 more
wiley   +1 more source

Relationship Between Sleep Disturbances and Non‐Odontogenic Orofacial Pain and Its Impact on Quality of Life: A Systematic Review With Narrative Synthesis

open access: yesAustralian Dental Journal, EarlyView.
Population: Adults with non‐odontogenic orofacial pain, including temporomandibular disorders (TMDs), burning mouth syndrome (BMS), post‐traumatic trigeminal neuropathy (PTTN), and other chronic non‐odontogenic orofacial pain referral cohorts. Exposure: Sleep disturbances assessed using the Pittsburgh Sleep Quality Index (PSQI), Basic Nordic Sleep ...
Jainy Shah   +3 more
wiley   +1 more source

Factors influencing HRQOL in children with FC.

open access: yes, 2013
Notes: (1) Multiple step-wise regression analysis was used to select factors that influenced the HRQOL in children with FC, using scores of physical, emotional, social, school, and the summary score of the Generic Core Scale as dependent variables.
Yuhai Zhang (220277)   +9 more
core   +1 more source

Efficacy of Full and Limited Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal Polyps: A Randomised Controlled Trial

open access: yesAllergy, EarlyView.
Both Full and Limited FESS result in clinically meaningful relief of disease‐specific HRQoL and nasal breathing, effectively improving nasal symptoms and sleep disturbance in CRSwNP patients. Clinically meaningful difference in decrease of SNOT‐22 scores between the groups was not found at 12‐ and 24–month follow‐up.
P. Virkkula   +10 more
wiley   +1 more source

Survey of the Actual Situation of HRQoL among Patients with Chronic Diseases at Community Pharmacies in Japan and Decision Tree Analysis of Patient Attributes Affecting HRQoL [PDF]

open access: yes
Objective: We investigated the health-related quality of life (HRQoL) of patients with chronic diseases in community pharmacies in Japan and examined its relationship to patient attributes, an area that has not been previously studied.
大島, 新司   +6 more
core   +1 more source

Improving the Understanding of Late Effects of Testicular Cancer in Adolescent and Young Adult Survivors: TRANSCEND‐XR

open access: yesAndrology, EarlyView.
ABSTRACT Background Testicular cancer (TC) is the most common malignancy amongst adolescents and young adults (AYAs) aged 15–39 years assigned male at birth. Survivors often experience late effects of treatment and report unmet supportive care needs.
Mohamad M. Saab   +30 more
wiley   +1 more source

Health-related quality of life in neobladder versus ileal conduit after robot-assisted radical cystectomy: A systematic review

open access: yes
reservedObiettivo: Lo scopo è di indagare come la qualità della vita correlata alla salute (Health Related Quality of Life - HRQoL) nei pazienti sottoposti a RARC (Robot-Assisted Radical Cystectomy) venga influenzata dal tipo di ricostruzione del ...
ESPOSITO, LUIGI
core  

Meta‐Analysis: The Placebo Response in Modern Treatments for Cholestatic Pruritus: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Placebo arms show substantial improvement in cholestatic pruritus, with up to 30% response rate. Estimates differed across outcome instruments, highlighting the importance of endpoint selection and realistic placebo assumptions in future trial design.
Igor Boechat Silveira   +8 more
wiley   +1 more source

Safety and Efficacy of 10 kHz Spinal Cord Stimulation for the Treatment of Refractory Chronic Migraine: A Prospective Long‐Term Open‐Label Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy   +7 more
wiley   +1 more source

Factors influencing the quality of life of children with epilepsy aged 2–4 years

open access: yesZdorovʹe Rebenka
Background. Epilepsy in early childhood can cause a significant developmental and psychosocial burden, yet the determinants of health-related quality of life (HRQoL) in patients aged 2–4 years remain inadequately characterized, especially in clinical ...
M.N.A. Apriansah   +3 more
doaj   +1 more source

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