Results 141 to 150 of about 78,174 (316)

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Clinical outcomes of the chemo‐free approach in relapsed/refractory follicular lymphoma: A network meta‐analysis

British Journal of Haematology, EarlyView.
Graphical overview of the network meta‐analysis (NMA) evaluating chemo‐free approaches for relapsed/refractory follicular lymphoma (R/R FL). Epcoritamab plus rituximab (R2) achieved the highest cumulative ranking probability (SUCRA) across efficacy end‐points but increases the risk of predictable toxicity over anti‐CD20 monotherapy.
Daniele Caracciolo, Maria Rita Lombardo, Gianluca Reitano, Cristina Napoli, Lucia Fiorillo, Chiara Callerame, Mario Garritano, Alessio Bulotta, Maha Munir, Giulia Pensabene, Emiliano Barbieri, Alberto Bavieri, Pierfrancesco Tassone, Pierosandro Tagliaferri, Stefano Luminari   +14 more
wiley   +1 more source

The ‘Prostate Cancer Screening for People at Genetic Risk of Aggressive Disease’ (PATROL) study

BJU International, EarlyView.
Background Inherited (germline) pathogenic and likely pathogenic variants (gPVs) in key genes associated with increased risk of prostate cancer (PCa) now warrant more attentive PCa screening per National Comprehensive Cancer Network (NCCN) guidelines—e.g., BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53.
Heather H. Cheng, Kara N. Maxwell, Keyan Salari, Matthew R. Cooperberg, Kristin Follmer, Joanne M. Jeter, Grace Jun, Daniel J. Lee, Hiten D. Patel, Edward M. Schaeffer, Alexandra O. Sokolova, Erika M. Wolff, Daniel W. Lin   +12 more
wiley   +1 more source

Health‐related quality of life and patient‐reported outcome measures in economic evaluation of urological technologies: challenges and opportunities

BJU International, EarlyView.
Objective To examine the role of health‐related quality of life (HRQoL) assessments and patient‐reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.
Mohammed El Bahnasawi, Charlotte Moss, Netty Kinsella, Kathie Alexina Wong, Mieke Van Hemelrijck   +4 more
wiley   +1 more source

Assessment of Health-Related Quality of Life Among Patients with Chronic Diseases and Its Relationship with Multimorbidity: A Cross-Sectional Study from Saudi Arabia

Patient Preference and Adherence
Abdulaziz Ibrahim Alzarea,1 Yusra Habib Khan,1 Sami I Alzarea,2 Abdullah Salah Alanazi,1 Omar Awad Alsaidan,3 Maily J Alrowily,4 Monefah Al-Shammari,5 Ziyad Saeed Almalki,6 Majed A Algarni,7 Tauqeer Hussain Mallhi1 1Department of Clinical Pharmacy ...
Alzarea AI, Khan YH, Alzarea SI, Alanazi AS, Alsaidan OA, Alrowily MJ, Al-Shammari M, Almalki ZS, Algarni MA, Mallhi TH   +9 more
doaj  

Examining the Psychometric Properties of the Ultra‐Short Version of the Oral Health Impact Profile in Australia

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives The Oral Health Impact Profile (OHIP) is the most widely used instrument to measure the subjective impact of oral conditions. This study reports the shortening and psychometric evaluation of an ultra‐short version (OHIP‐7A) from the OHIP‐14 in a large national Australian population.
Brandan Khor, Gustavo Hermes Soares, Dandara Gabriela Haag, Gloria Mejia, Liana Luzzi, Lisa Jamieson, Pedro Henrique Ribeiro Santiago   +6 more
wiley   +1 more source

Treatment Adherence and Health-Related Quality of Life Among Patients with Hypertension at Tertiary Healthcare Facility in Lalitpur, Nepal: A Cross-Sectional Study

Patient Preference and Adherence
Binita Rupakheti,1 Badri KC,1 Durga Bista,1 Sunayana KC,1 Kashi Raj Pandey2 1Department of Pharmacy, School of Science, Kathmandu University, Dhulikhel, Kavrepalanchowk, Nepal; 2Department of Languages and Mass Communication, School of Arts, Kathmandu ...
Rupakheti B, KC B, Bista D, KC S, Pandey KR   +4 more
doaj  

Factors Associated With Parent‐Reported Caries in Preschool Children From the KUNO‐Kids Health Study—Repeated Cross‐Sectional Analysis

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives This questionnaire‐based study aimed to assess parent‐reported caries (PRC) at ages 2–5 years and identify potential influencing factors using an exploratory, repeated cross‐sectional analysis within an ongoing birth‐cohort study.
Áine M. Lennon, Katharina Fluch‐Maier, K.‐A. Hiller, Isabelle Schenke, Nils Gade, W. Buchalla, Susanne Brandstetter, Angela Köninger, Michael Melter, Christian Apfelbacher, Michael Kabesch, KUNO‐Kids Study group, Andreas Ambrosch, Petra A. Arndt, Andrea Baessler, Mark Berneburg, Romuald Brunner, Sara Fill Malfertheiner, André Franke, Stephan Gerling, Iris Heid, Stefanie Heinze, Wolfgang Högler, Sebastian Kerzel, Michael Koller, Michael Leitzmann, Áine Lennon, David Rothfuß, Martin Promm, Bianca Schaub, Stephan Weidinger, Sven Wellmann   +31 more
wiley   +1 more source

How do doctors integrate HRQoL data into oncology consultations? [PDF]

Aims To explore how oncologists integrate HRQoL data into consultations with patients and identify good practice in discussing HRQoL data in consultations.
Greenhalgh, Joanne, Abhyankar, Purva, Takeuchi, Elena, McCluskey, Serena, Velikova, Galina   +4 more
core  

HRQOL and subjective well-being: noncomplementary forms of outcome measurement [PDF]

, 2004
This review considers some of the broad principles that concern quality of life assessment. These are discussed in relation to health-related quality of life (HRQOL) and the measurement of subjective well-being.
Robert Cummins (13065627), Mark Stokes (13096311), Anna Lau (13088406)   +2 more
core