Results 61 to 70 of about 29,680 (309)
British Journal of Clinical Pharmacology, EarlyView.Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić +4 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Međunarodne Studije, 2013 Općeprihvaćena je teza u javnom političkom diskursu da je proces pridruživanja Hrvatske Europskoj Uniji i NATO-u djelovao stabilizirajuće i poticajno na procese političke, gospodarske i sigurnosne transformacije zemlje.
Jadranka Polović
doaj
British Journal of Clinical Pharmacology, EarlyView.Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić +8 more
wiley +1 more source
Influence of long maceration on the quality of Graševina wine in Kutjevo wine-growing hill
Glasnik Zaštite Bilja, 2022 Although classical production of white wines involves the fermentation of must, recently there has been a trend in the production of white wines with maceration processor fermentation of pomace. The aim of this paper is to determine the influence of long
Valentina Obradović +5 more
doaj
Filologija, 1997 In Croatian texts and dictionaries from XVI-XVIII centuries, a word for a sword maker and cleaner was 'cestar', 'cistar'. Vladimir Mažuranić connected the word with the Old Church Slavonic verb *cĕstiti 'to clean'. The article confirms Mažuranić's etymology.
openaire +2 more sources
, 1993 Iznose se osnovna načela odgovornosti za naknadu štete od onečišćenja naftom Konvencije o odgovornosti iz 1969 i Konvencije o fondu iz 1971. kao i promjene koje su izvršene Protokolima iz 1976., 1984. i 1992. godine.
Velimir Filipović
core
British Journal of Clinical Pharmacology, EarlyView.Aims The Black Triangle Scheme, introduced in 2018 in Australia, does not appear to have increased the quantity of adverse drug event (ADE) reports. This study evaluated healthcare professionals' (HCPs') and consumers' awareness of the scheme, its influence on intentions for future ADE reporting, and suggested improvements.
Eyob Alemayehu Gebreyohannes +7 more
wiley +1 more source