Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti +2 more
wiley +1 more source
Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright +9 more
wiley +1 more source
冠心病患者NT-ProBNP与HS-CRP联合检测的临床意义
目的探讨冠心病患者中NT-proBNP与hs-CRP联合检测的临床意义。方法收集临床上冠心病患者并进行分组,其中AMI组25例,UA组20例,SA组25例;正常对照组10例,所有患者入院后均即刻进行NT-proBNP与hs-CRP的检测,并根据NT-proBNP与hs-CRP高低再进一步将所有患者分成低NT-proBNP/低hs-CRP;低NT-proBNP/高hs-CRP;高NT-proBNP/低hs-CRP;高NT-proBNP/高hs-CRP四组。结果高NT-proBNP/高hs ...
宋春莉, 刘斌, 费瑜, 陈宏勃
doaj
New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender +2 more
wiley +1 more source
Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study [PDF]
AIMS/HYPOTHESIS: Vasopressin plays a role in osmoregulation, glucose homeostasis and inflammation. Therefore, plasma copeptin, the stable C-terminal portion of the precursor of vasopressin, has strong potential as a biomarker for the cardiometabolic ...
A Abbasi +47 more
core +4 more sources
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang +9 more
wiley +1 more source
Background: To evaluate the association between pre/post-procedural high sensitive C-reactive protein (hs-CRP) level and hs-CRP difference, and the risk of major adverse cardiovascular events (MACE) or new diffusion-weighted MRI lesions after carotid ...
Farzaneh Foroughinia +4 more
doaj
A comparative study of the correlations of the COPD assessment test (CAT) scores and high sensitive CRP levels to SPO2, FEV1, BODE index, and exacerbation rate. [PDF]
Background: High sensitive CRP is used as a marker of systematic inflammation in COPD. Results have shown an inverse relation between serum hs-CRP and FEV1, except for small study which did not report any correlation between hs-CRP level and FEV1 ...
بیوک آقازاده, کاترین +2 more
core
The interaction between a HSP-70 gene variant with dietary calories in determining serum markers of inflammation and cardiovascular risk [PDF]
Background: The high prevalence of cardiovascular disease (CVD) globally is attributable to an interaction between environmental and genetic factors.
Avan, Amir +13 more
core +1 more source
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang +10 more
wiley +1 more source

