Results 211 to 220 of about 63,749 (300)

Derivation and validation of the Pediatric Community‐Acquired Pneumonia Severity (PedCAPS) score: A prospective cohort study

open access: yesJournal of Hospital Medicine, Volume 21, Issue 5, Page 590-598, May 2026.
Abstract Introduction Community‐acquired pneumonia (CAP) is a frequent and costly cause of pediatric emergency department (ED) visits and hospitalizations. Previous prognostic tools for CAP are limited by small samples, single‐center or retrospective designs, lack of generalizability to ED settings, lack of biomarkers, or limited objective data.
Todd A. Florin   +21 more
wiley   +1 more source

Risk of Crohn's disease in children presenting with perianal abscess and fistula increases with age: A multicenter study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 5, Page 1226-1232, May 2026.
Abstract Objectives Perianal abscesses (PA) and fistulas‐in‐ano (FIA) are frequently diagnosed in children and may be presenting symptoms of Crohn's disease (CD). The association between age at presentation of PA/FIA and the risk of subsequent CD development is largely unknown.
Mariëlle Roskam   +13 more
wiley   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, Volume 61, Issue 3, Page 319-329, May 2026.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, Volume 45, Issue 3, Page 455-475, May/June 2026.
ABSTRACT Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

A Case of Anti‐AMY1‐Positive Lung Squamous Cell Carcinoma With Severe Hyperamylasemia Linked to Disease Progression

open access: yesRespirology Case Reports, Volume 14, Issue 5, May 2026.
We present a case of anti‐AMY1‐positive lung squamous cell carcinoma (LUSC) with severe hyperamylasemia. To our knowledge, no previous cases of LUSC have been reported with both histological evidence of amylase production and hyperamylasemia. This case provides new evidence that LUSC can produce amylase and cause hyperamylasemia. ABSTRACT A 74‐year‐old
Yusuke Nakamura   +10 more
wiley   +1 more source

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