Results 141 to 150 of about 1,000 (162)

Identification and Characterization of the 28-N-Methyltransferase Involved in HSAF Analogue Biosynthesis

Biochemistry, 2022
Polycyclic tetramate macrolactams (PoTeMs) are a family of structurally intriguing bioactive natural products. Although the presence of the N-28 methyl group is known to affect bioactivities of some PoTeMs, the mechanism for this methylation remains unclear.
Jie Luo   +5 more
openaire   +2 more sources

Biosynthesis of Odd-Carbon Unsaturated Fatty Dicarboxylic Acids Through Engineering the HSAF Biosynthetic Gene in Lysobacter enzymogenes

Molecular Biotechnology, 2022
Fatty dicarboxylic acids (FDCA) are useful as starting materials or components for plastics, polyesters, nylons, and fragrances. Most of the commercially available FDCA contain an even number of carbons, and there remain few sustainable methods for production of FDCA with an odd number of carbons (o-FDCA). In this work, we explored a novel biosynthetic
Vimmy Khetrapal   +2 more
openaire   +2 more sources

3-Hydroxylation of the polycyclic tetramate macrolactam in the biosynthesis of antifungal HSAF from Lysobacter enzymogenes C3

MedChemComm, 2012
HSAF isolated from Lysobacter enzymogenes is an antifungal natural product with a new mode of action. The polycyclic tetramate macrolactam (PTM) carries a 3-hydroxyl group on the ornithine residue, which is a feature common to nearly all PTM type natural products found in phylogenetically diverse organisms.
Yaoyao Li   +4 more
openaire   +1 more source

Using the Jupyter Notebook as a Tool for analyzing the EUMETSAT HSAF snow products

2020
<p>Snow cover is an essential climate variable directly affecting the Earth’s energy balance, therefore estimating the snow parameters play an important role in hydrological, land surface, meteorological and climate models.
Zuhal Akyurek   +3 more
openaire   +1 more source

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