Results 11 to 20 of about 593 (166)

LeTetR Positively Regulates 3-Hydroxylation of the Antifungal HSAF and Its Analogs in Lysobacter enzymogenes OH11 [PDF]

Molecules, 2020
The biocontrol agent Lysobacter enzymogenes OH11 produces several structurally distinct antibiotic compounds, including the antifungal HSAF (Heat Stable Antifungal Factor) and alteramides, along with their 3-dehydroxyl precursors (3-deOH).
Lingjun Yu, Vimmy Khetrapal, Fengquan Liu, Liangcheng Du   +3 more
doaj   +4 more sources

Spermidine-Regulated Biosynthesis of Heat-Stable Antifungal Factor (HSAF) in Lysobacter enzymogenes OH11 [PDF]

Frontiers in Microbiology, 2018
Heat-Stable Antifungal Factor (HSAF) and its analogs are antifungal natural products produced by the biocontrol agent Lysobacter enzymogenes. The production of HSAF is greatly influenced by environmental stimuli and nutrients, but the underlying ...
Yuan Chen, Yuan Chen, Lingjun Yu, Lingjun Yu, Fengquan Liu, Liangcheng Du   +5 more
doaj   +5 more sources

LesR is a novel upstream regulator that controls downstream Clp expression to modulate antibiotic HSAF biosynthesis and cell aggregation in Lysobacter enzymogenes OH11 [PDF]

Microbial Cell Factories, 2017
Background Heat-stable antifungal factor (HSAF) is a polycyclic tetramate macrolactam secondary metabolite that exhibits broad-spectrum inhibitory activities against filamentous fungal pathogens. The native yield of this chemical is low.
Huiyong Xu, Ruping Wang, Yangyang Zhao, Zheng Qing Fu, Guoliang Qian, Fengquan Liu   +5 more
doaj   +4 more sources

Identification and Characterization of the 28‑N‑Methyltransferase Involved in HSAF Analogue Biosynthesis

Biochemistry, 2022
Polycyclic tetramate macrolactams (PoTeMs) are a family of structurally intriguing bioactive natural products. Although the presence of the N-28 methyl group is known to affect bioactivities of some PoTeMs, the mechanism for this methylation remains ...
Haoxin Wang (1425376), Yaoyao Li (425792), Jie Luo (95251), Yuemao Shen (138504), Xue Li (285380), Liangcheng Du (425795)   +5 more
core   +3 more sources

Genome Mining and Metabolic Profiling Uncover Polycyclic Tetramate Macrolactams from Streptomyces koyangensis SCSIO 5802 [PDF]

Marine Drugs, 2021
We have previously shown deep-sea-derived Streptomyces koyangensis SCSIO 5802 to produce two types of active secondary metabolites, abyssomicins and candicidins. Here, we report the complete genome sequence of S.
Wenjuan Ding, Jiajia Tu, Huaran Zhang, Xiaoyi Wei, Jianhua Ju, Qinglian Li   +5 more
doaj   +2 more sources

Hfq modulates system-wide regulatory networks controlling biocontrol property in Lysobacter enzymogenes [PDF]

Synthetic and Systems Biotechnology
Lysobacter enzymogenes is a beneficial soil bacterium renowned for its potent biocontrol properties, primarily attributed to antimicrobial secondary metabolites such as HSAF and WAP-8294A2, as well as specialized secretion systems.
Xinyi Cheng, Wenhui Chen, Yangyang Zhao, Yancun Zhao, Fengquan Liu, Gaoge Xu   +5 more
doaj   +2 more sources

The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner [PDF]

Communications Biology, 2021
Li et al shows that the quorum sensing system component protein RpfG from Lysobacter, in addition to being a cyclic dimeric GMP (c-di-GMP) phosphodiesterase, also regulates the biosynthesis of an antifungal factor.
Kaihuai Li, Gaoge Xu, Bo Wang, Guichun Wu, Rongxian Hou, Fengquan Liu   +5 more
doaj   +2 more sources

Performance of Hammerstein Spline Adaptive Filtering Based on Fair Cost Function for Denoising Electrocardiogram Signals [PDF]

Biomimetics
This paper proposes a simplified adaptive filtering approach using a Hammerstein function and the spline interpolation based on a Fair cost function for denoising electrocardiogram (ECG) signals.
Suchada Sitjongsataporn, Theerayod Wiangtong   +1 more
doaj   +2 more sources

Genetic Basis and Expression Pattern Indicate the Biocontrol Potential and Soil Adaption of Lysobacter capsici CK09 [PDF]

Microorganisms, 2023
Lysobacter species have attracted increasing attention in recent years due to their capacities to produce diverse secondary metabolites against phytopathogens.
Pu Yang, Chaofan Qu, Miaomiao Yuan, Bo Xi, Xiu Jia, Ben Zhang, Lizhen Zhang   +6 more
doaj   +2 more sources

Iterative Assembly of Two Separate Polyketide Chains by the Same Single-module Bacterial Polyketide Synthase in the Biosynthesis of HSAF [PDF]

Angewandte Chemie, 2014
HSAF (1) was isolated from the biocontrol agent Lysobacter enzymogenes (Figure 1).[1-4] This bacterial metabolite belongs to polycyclic tetramate macrolactams (PTM) that are emerging as a new class of natural products with distinct structural features ...
Cerny, Ronald, Liangcheng Du, Chen, Haotong, Yaoyao Li, Haotong Chen, Xie, Yunxuan, Du, Liangcheng, Ronald L. Cerny, Yuemao Shen, Haoxin Wang, Ding, Yanjiao, Yunxuan Xie, Li, Yaoyao, Shen, Yuemao, Wang, Haoxin, Yanjiao Ding   +15 more
core   +4 more sources