Spermidine-Regulated Biosynthesis of Heat-Stable Antifungal Factor (HSAF) in Lysobacter enzymogenes OH11 [PDF]
Frontiers in Microbiology, 2018 Heat-Stable Antifungal Factor (HSAF) and its analogs are antifungal natural products produced by the biocontrol agent Lysobacter enzymogenes. The production of HSAF is greatly influenced by environmental stimuli and nutrients, but the underlying ...
Fengquan Liu +2 more
exaly +5 more sources
LeTetR Positively Regulates 3-Hydroxylation of the Antifungal HSAF and Its Analogs in Lysobacter enzymogenes OH11 [PDF]
Molecules, 2020 The biocontrol agent Lysobacter enzymogenes OH11 produces several structurally distinct antibiotic compounds, including the antifungal HSAF (Heat Stable Antifungal Factor) and alteramides, along with their 3-dehydroxyl precursors (3-deOH).
Lingjun Yu +3 more
doaj +3 more sources
An Antifungal Polycyclic Tetramate Macrolactam, Heat-Stable Antifungal Factor (HSAF), Is a Novel Oxidative Stress Modulator in Lysobacter enzymogenes [PDF]
Applied and Environmental Microbiology, 2021 PoTeMs are a family of structurally distinct metabolites that have been found in a large number of bacteria. Although PoTeMs exhibit diverse therapeutic properties, the physiological function of PoTeMs in the producer microorganisms had not been investigated.
Fengquan Liu, Hui Li, Zaichun Zhou
exaly +5 more sources
Hijacking competitor-derived signals: RcsB/C drives Lysobacter enzymogenes to exploit farnesol for enhanced antifungal capacity [PDF]
Applied and Environmental MicrobiologyMicrobial antagonism is a fundamental ecological process that shapes community composition and maintains ecosystem balance. However, the molecular signals, such as cross-kingdom interactions between bacteria and fungi in natural environments, remain ...
Fang Nan +7 more
doaj +2 more sources
Hfq modulates system-wide regulatory networks controlling biocontrol property in Lysobacter enzymogenes [PDF]
Synthetic and Systems BiotechnologyLysobacter enzymogenes is a beneficial soil bacterium renowned for its potent biocontrol properties, primarily attributed to antimicrobial secondary metabolites such as HSAF and WAP-8294A2, as well as specialized secretion systems.
Xinyi Cheng +5 more
doaj +2 more sources
The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner [PDF]
Communications Biology, 2021 Li et al shows that the quorum sensing system component protein RpfG from Lysobacter, in addition to being a cyclic dimeric GMP (c-di-GMP) phosphodiesterase, also regulates the biosynthesis of an antifungal factor.
Kaihuai Li +5 more
doaj +2 more sources
Performance of Hammerstein Spline Adaptive Filtering Based on Fair Cost Function for Denoising Electrocardiogram Signals [PDF]
BiomimeticsThis paper proposes a simplified adaptive filtering approach using a Hammerstein function and the spline interpolation based on a Fair cost function for denoising electrocardiogram (ECG) signals.
Suchada Sitjongsataporn +1 more
doaj +2 more sources
Genetic Basis and Expression Pattern Indicate the Biocontrol Potential and Soil Adaption of Lysobacter capsici CK09 [PDF]
Microorganisms, 2023 Lysobacter species have attracted increasing attention in recent years due to their capacities to produce diverse secondary metabolites against phytopathogens.
Pu Yang +6 more
doaj +2 more sources
Expanding Polycyclic Tetramate Macrolactam (PoTeM) Core Structure Diversity by Chemo-Enzymatic Synthesis and Bioengineering. [PDF]
Angew Chem Int Ed EnglPolycyclic tetramate macrolactams (PoTeMs) derive from ornithine‐based lysobacterene A. To expand the PoTeM core structure carbon skeleton by a CH2‐unit, a synthetic access to lysobacterene A and an extended analog was developed, and cyclization by cognate ikarugamycin cyclases IkaBC was achieved in vitro.
Schuler S +6 more
europepmc +2 more sources
Coordinated control of the type IV pili and c-di-GMP-dependent antifungal antibiotic production in Lysobacter by the response regulator PilR. [PDF]
Mol Plant Pathol, 2021 PilR phosphorylation mediated by PilS down‐regulates lchD expression via DNA binding to lower c‐di‐GMP synthesis and thus accumulate c‐di‐GMP‐free Clp, which activates heat‐stable antifungal factor production via DNA binding. Abstract In the soil gammaproteobacterium Lysobacter enzymogenes, a natural fungal predator, the response regulator PilR ...
Xu K +5 more
europepmc +2 more sources