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HPV 6-associated HSIL/Squamous Carcinoma in the Anogenital Tract
International Journal of Gynecological Pathology, 2019Human papillomavirus (HPV) type 6 is historically classified as low-risk HPV type and associates with low-grade squamous intraepithelial lesions of the anogenital tract. Rare squamous carcinomas have been reported in association with these HPV types but the mechanism(s) behind this carcinogenic sequence have been unclear.
Martina Z, Liu +5 more
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HSIL Colposcopy Image Segmentation Using Improved U-Net
2021 36th Youth Academic Annual Conference of Chinese Association of Automation (YAC), 2021The screening and diagnosis of cervical lesions can effectively reduce the risk of cervical cancer. At present, there are few research algorithms and models for colposcopy in cervical lesion image segmentation. If image about colposcopy can be directly used to automatically segment the precancerous lesion area of cervical cancer, it will help doctors ...
Juanqin Liu +3 more
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Overdiagnosis of HSIL on cervical biopsy: errors in p16 immunohistochemistry implementation
Human Pathology, 2016In 2012, the lower anogenital squamous terminology (LAST) project introduced new nomenclature for human papillomavirus-related squamous lesions of the lower genital tract: low-grade and high-grade squamous intraepithelial lesion (LSIL and HSIL). Biomarker p16(INK4a) immunohistochemistry (IHC) was also recommended to assist classification: block-like ...
Jennifer L, Clark +3 more
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HSIL, epithelial cell abnormality‐adjusted workload, and the Thinprep imaging system
Diagnostic Cytopathology, 2010AbstractPrevious studies have suggested that the sensitivity of the ThinPrep Imaging System (TIS) for high‐grade intraepithelial lesion (HSIL) and worse may be decreased at workloads above 100 slides/day. On the other hand, at a threshold of atypical squamous cells of undetermined significance (ASCUS) and above, sensitivity of the TIS appears to more ...
Andrew A, Renshaw, Tarik M, Elsheikh
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Cytology and outcome of LSIL: cannot exclude HSIL compared to ASC‐H
Cytopathology, 2009Objective: The cytological features associated with clinical outcome of ‘LSIL cannot exclude HSIL (LSIL‐H)’ in comparison with ‘atypical squamous cells cannot exclude HSIL (ASC‐H)’ are incompletely described.Methods: LSIL‐H and ASC‐H Pap tests reported in a regional laboratory during a 13‐month period were reviewed by two pathologists.
C, Hunter +5 more
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Genotypes and prevalence of HPV single and multiple concurrent infections in women with HSIL
Diagnostic Cytopathology, 2014The contribution of human papillomavirus (HPV) types to the carcinogenesis of cervical cancer has been established for a long time. However, the role of phylogenetically related and rare variants remains uncertain, as well as the influence of concurrent multiple HPV genotypes infection.
Francisco, Beca +4 more
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Management of HSIL — authors' reply
International Journal of STD & AIDS, 2004K Manavi, A McMillan
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HSIL cervical tests: can we omit colposcopy?
Obstetrics & Gynecology, 2000Abstract Objective: To determine whether patients with high-grade intraepithelial lesions (HSIL) on Pap test can omit colposcopic examination and proceed directly to therapeutic loop excision. Methods: Sixty-eight women referred with an HSIL on Pap test were prospectively evaluated by a standard treatment protocol that included repeat cytology and ...
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Accuracy of In Vivo Light Scattering for Detection of HSIL and Cancers of the Cervix.
Biomedical Optics, 2008In vivo light scattering data have been analyzed for 151 patients. Physiological parameters correlate with light scattering. Sensitivities in the 80's and specificities in the 60's were obtained for a disease threshold of HSIL+.
Judith R. Mourant +7 more
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