Results 41 to 50 of about 18,501 (187)

Directions for Improving the Laboratory Component in Secondary Prevention of Cervical Cancer

Эпидемиология и вакцинопрофилактика
Relevance. Effective responses are required due to the high incidence of cervical cancer (Cc) throughout the World. RT-PCRbased HPV-testing is becoming more prominent in secondary prevention worldwide, replacing cytology. Russian practice still relies on
O. B. Kuleshova, E. A. Domonova, G. N. Minkina, T. N. Romanuk, A. N. Gerasimov, E. M. Voronin, V. G. Akimkin   +6 more
doaj   +1 more source

The performance of anal cytology as a screening test for anal HSILs in homosexual men [PDF]

Cancer Cytopathology, 2016
BACKGROUNDStudies regarding the performance of anal cytology in which both the screening test (cytology) and the diagnostic test (high‐resolution anoscopy [HRA]) are performed in all members of a screening population are rare. The authors evaluated the performance of liquid‐based anal cytology in a cohort of homosexual men in Sydney, New South Wales ...
Jin, F, Grulich, AE, Poynten, IM, Hillman, RJ, Templeton, DJ, Law, CLH, Farnsworth, A, Garland, SM, Fairley, CK, Roberts, JM   +9 more
openaire   +3 more sources

Triage Performance of FAM19A4/miR124‐2 Methylation: 18‐Month Follow‐Up Results From a Prospective Observational Study Within the Dutch Primary HPV‐Based Cervical Screening Program

International Journal of Cancer, EarlyView.
ABSTRACT DNA methylation analysis of the genes FAM19A4 and miR124‐2 has emerged as a promising triage strategy for high‐risk (hr) human papillomavirus (HPV)‐positive women in cervical screening. This study reports a prospective evaluation of the diagnostic accuracy of FAM19A4/miR124‐2 methylation in a large population‐based primary HPV‐based screening ...
Lisanne Verhoef, Mila S. Griffioen, Maaike C. G. Bleeker, John W. J. Hinrichs, Albert G. Siebers, Albertus T. Hesselink, Chris J. L. M. Meijer, Renske D. M. Steenbergen, Johannes Berkhof, Daniëlle A. M. Heideman   +9 more
wiley   +1 more source

Correlation between HPV16 positivity on anal swab and biopsy-confirmed HSIL caused by HPV16 in the study of the prevention of anal cancer (SPANC)

Papillomavirus Research, 2018
Background: The majority of anal carcinomas are caused by human papillomavirus (HPV) 16. Identifying which of the high-grade squamous intraepithelial lesions (HSIL) are caused by HPV16 may enable targeted management of those most likely to progress ...
Jennifer M. Roberts, Monica Molano, Julia K. Thurloe, Richard J. Hillman, David J. Templeton, Carmella Law, I. Mary Poynten, Fengyi Jin, Patricia Guzman, Suzanne M. Garland, Dorothy A. Machalek, Andrew E. Grulich, Alyssa M. Cornall   +12 more
doaj   +1 more source

Yield of endocervical curettage in detecting cervical intraepithelial neoplasia grade 2 or higher during colposcopy: A prospective, cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 105-111, April 2025.
Abstract Objective This study assessed the prevalence and factors associated with detecting cervical intraepithelial neoplasia grade 2 or higher (CIN2+) via endocervical curettage (ECC) during colposcopy. Methods Between December 2020 and September 2023, a prospective, cross‐sectional study involving women with abnormal cervical cancer screening ...
Nida Jareemit, Lalita Theerarojanapong, Natthawadee Laokulrath, Vuthinun Achariyapota, Khemanat Khemworapong, Sompop Kuljarasnont, Pornporm Ittiamornlert, Vitcha Poonyakanok, Perapong Inthasorn   +8 more
wiley   +1 more source

Use of human papillomavirus DNA, E6/E7 mRNA, and p16 immunocytochemistry to detect and predict anal high-grade squamous intraepithelial lesions in HIV-positive and HIV-negative men who have sex with men. [PDF]

PLoS ONE, 2013
Men who have sex with men (MSM) are at high risk of having anal cancer. Anal high-grade squamous intraepithelial lesion (HSIL) is the precursor of anal cancer.
Nittaya Phanuphak, Nipat Teeratakulpisarn, Somboon Keelawat, Tippawan Pankam, Jiranuwat Barisri, Surang Triratanachat, Amornrat Deesua, Piyanee Rodbamrung, Jiratchaya Wongsabut, Patou Tantbirojn, Saranya Numto, Preecha Ruangvejvorachai, Praphan Phanuphak, Joel M Palefsky, Jintanat Ananworanich, Stephen J Kerr   +15 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

A clinical and radiographic evaluation of immediately loaded fixed full-arch prosthesis supported by implants placed in extraction sockets and healed ridges using All-on-4/All-on-6 protocol: A 2-year follow-up

The Journal of Indian Prosthodontic Society
Aim: The aim of this study was to evaluate immediately loaded implants, both clinically and radiographically, in extraction sites (IPIL) and healed sites (HSIL), rehabilitated using All-on-4/All-on-6 protocol, over a time span of 2 years.
Nitin Sethi, Princy Agarwal, Parikshit Gupt   +2 more
doaj   +1 more source

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino, Sophie Jones, Nicholas Reid Caldwell, Catherine Cartwright, Benedict Blacket, Richard Clive Turner   +5 more
wiley   +1 more source