Results 41 to 50 of about 9,393 (131)

Health care policy trial of primary human papillomavirus–based cervical screening in Denmark: Comparison of three triage algorithms

International Journal of Cancer, Volume 158, Issue 12, Page 3197-3207, 15 June 2026.
What's new? Primary human papillomavirus (HPV)–based screening has shown superiority to cytology‐based screening in reducing cervical cancer risk in clinical trials. However, the benefit must be balanced with potential overdiagnosis/overtreatment.
Jeppe Bennekou Schroll, Jesper Bonde, Elsebeth Lynge, Marianne Waldstrøm, Petra Hall Viborg, Anna Frandsen, Rikke Holst Andersen, Susanne Merete Nielsen, Bettina Kjær Kristensen, Doris Schledermann, Berit Andersen, on behalf ofthe National Danish Cervical Cancer Screening Steering Committee   +11 more
wiley   +1 more source

Impact of CD40 gene polymorphisms on the risk of cervical squamous cell carcinoma: a case-control study

BMC Cancer, 2023
Background Cervical cancer is the fourth most common cancer among women worldwide. Genome-wide association studies have revealed multiple susceptible genes and their polymorphisms for cervical cancer risk.
Manning Zhu, Xiaoying Li, Yanan Feng, Tianshuang Jia, Songxue Li, Liping Gong, Shuang Dong, Xianchao Kong, Litao Sun   +8 more
doaj   +1 more source

FEN1 plays a key role in the transition from HSIL to CSCC

Scientific Reports
Cervical high-grade squamous intraepithelial lesion (HSIL) is a well-recognized precursor to cervical squamous cell carcinoma (CSCC). This study aims to explore molecular mechanisms underlying this transition.
Fengxian Zhang, Xiaomei Chen, Chenyang Chu, Meilin Chen, Ying Yang, Yanting You, Jie Zhou, Pingping Jiang, Ni Song, Yunhong Yu, Yanyan Liu   +10 more
doaj   +1 more source

Rare widespread dissemination of cervical high-grade squamous intraepithelial lesion with microinvasive squamous cell carcinoma: a case report

Frontiers in Oncology
BackgroundCervical high-grade squamous intraepithelial lesion (HSIL), a precancerous condition, can progress to cervical squamous cell carcinoma (CSCC), the most prevalent histological subtype of cervical cancer.
Shijie Liu, Dan Liu
doaj   +1 more source

The Role of Enterococcus faecium in the Synergistic Clearance of High‐Risk HPV: A Clinical Study on Cervicovaginal Microbiota Regulation

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Persistent infection with high‐risk human papillomavirus (HR‐HPV) is defined as the principal cause of cervical cancer. Given the important role of cervicovaginal microbiota in HPV acquisition and disease progression, this study aims to evaluate the clinical efficacy of the probiotic Enterococcus faecium (E.
Jun Yang, Mengya Gao, Danfeng Wang, Ziwei Li, Sijing Li, Min Zhou, Li‐Na Hu   +6 more
wiley   +1 more source

Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad, Narges Eslami, Kaveh Gharaei Nejad, Atefeh Zamani Kermanshahi, Hossein Bannazadeh Baghi   +4 more
wiley   +1 more source

Cytomorphological analysis of cervical Pap smear findings - a hospital based retrospective study [PDF]

New Indian Journal of OBGYN
Background: Cervical cancer remains a major cause of cancer related mortality among women, particularly in low resource settings. The Papanicolaou (Pap) smear, interpreted using the Bethesda system, is an effective tool for early detection of ...
Ninza Das , Chandan Jyoti Saikia , Susmita Sarma , Hemakanta Dev Sarma , Balmiki Datta   +4 more
doaj   +1 more source

Association of Cervical Screening Results with Colposcopic Findings

Bagcilar Medical Bulletin, 2020
Objective:Cervical cancer is the fourth most common female cancer. In addition to early cancer diagnosis, the screening strategy of cervical cancer is based on early diagnosis of precancerous lesions [high-grade cervical lesions (HSIL)] to prevent cancer
Derya Kılıç, Tolga Güler
doaj   +1 more source

Primary Cancer Prevention Through Vaccination: Advances, Challenges, and Global Perspectives

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Oncogenic viral and bacterial infections constitute a significant portion of the global cancer burden, accounting for up to 15% of cases, particularly in low‐ and middle‐income countries. Prophylactic vaccination thus appears to be the most effective tool for preventing these preventable cancers, especially those linked to human papillomavirus
Christian Tague, Johan Domga, Ayesha Junaid, Okhesomi Rejoice Eshemokhai, Josias Kamgang Silatchom, Criss Koba Mjumbe   +5 more
wiley   +1 more source

Diagnostic Accuracy of Entropy Based Image Analysis of Cervical Precancerous Cells

Journal of Biophotonics, Volume 19, Issue 6, June 2026.
This work studies the correlation between the Bragg‐Williams order parameter (S2), as measured from a digital slide image, and the cytopathologic diagnoses of squamous cervical cytology and demonstrates the diagnostic accuracy of the S2 classification model. This image is an example of this approach for a “carcinoma in situ” cell image and demonstrates
Jennifer Makin, Esther Elishaev, Steven M. Durbin, Robert A. Makin   +3 more
wiley   +1 more source