Results 201 to 210 of about 158,688 (339)

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Unraveling the Molecular Inhibition and Conformational Changes of Hsp70 and Hsc70 Induced by VER-155008, a Competitive ATPase Inhibitor through Molecular Dynamics Simulations and Principal Component Analysis. [PDF]

ACS Omega
Barbosa da Silva MC, Falabelo CGS, Leonardo ES, Oliveira C, Valente RPDP, Lima AH, Farias SAS, Nagata K, da Costa KS, Taube PS.   +9 more
europepmc   +1 more source

Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters

Andrology, EarlyView.
ABSTRACT Background Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on the effects of EVs on spermatozoa have focused on ejaculated spermatozoa, which have already been exposed to their own native
Ana Moya‐Fernández, Santa María Toledo‐Guardiola, Peter Silke, Sergio Navarro‐Serna, Carmen Matás   +4 more
wiley   +1 more source

Therapeutic targets in diabetic peripheral neuropathy: heat shock proteins. [PDF]

Front Endocrinol (Lausanne)
Yin C, Lv J, Huang S, Lang C, Zhao Y, Wang G, Kan J, Wang X.   +7 more
europepmc   +1 more source

HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD‐1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma [PDF]

, 2006
Hui Geng, Guimei Zhang, Xiao Han, Ye Yuan, Dong Li, Hui Zhang, Hui Qiu, Yufei He, Zuo‐Hua Feng   +8 more
openalex   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Characterization and Evolutionary Analysis of Non-Canonical Heat Shock Protein 70 Family Members in Metazoan. [PDF]

Int J Mol Sci
Tan J, Li X, Wang Q, Xu W, Liu J, He Y, Yin W, Li J, Li X, Song X, Xu K, Wang G.   +11 more
europepmc   +1 more source

Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2

, 2020
Zhen Xu, Richard C. Page, Michelle M. Gomes, Ekta Kohli, Jay C. Nix, Andrew B. Herr, Cam Patterson, Saurav Misra   +7 more
openalex   +1 more source

Activity of the yeast cytoplasmic Hsp70 nucleotide-exchange factor Fes1 is regulated by reversible methionine oxidation [PDF]

, 2019
Erin E. Nicklow, Carolyn S. Sevier
openalex   +1 more source

Estimated seroprevalence of Ehrlichia canis in dogs in a remote community in the Northern Territory, Australia

Australian Veterinary Journal, EarlyView.
Background The emergence of Ehrlichia canis in northern Australia in 2020 has reshaped the landscape of tick‐borne diseases in dogs, particularly in rural and remote communities where the brown dog tick (Rhipicephalus linnaei) is endemic. Despite the rapid spread of ehrlichiosis and reported impacts on dog health, its prevalence remains poorly ...
E Shepherdson, K Doust, JH Hoopes, AD Barbosa, J McNeill   +4 more
wiley   +1 more source