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2013
Aging or senescence in biology is defined as the process of gradual loss of important body functions and cells, and in particular, the inability of cells to reproduce and cope with stress. Important features of an aging cell include the progressive accumulation of damaged proteins, abnormal protein aggregates and oxidative stress.
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Aging or senescence in biology is defined as the process of gradual loss of important body functions and cells, and in particular, the inability of cells to reproduce and cope with stress. Important features of an aging cell include the progressive accumulation of damaged proteins, abnormal protein aggregates and oxidative stress.
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2010
??i??????i????i ????i???? ??i????i?? ?????????????????? ???????? Hsp70 ???? Hsp90 ?? ??????????i?? ????????????????i?? ???????????? ???? ???????????????????????? ??i?? ??i??????????????i??????i?? (3, 7, 10 i 14g) ?????????????? ?? ?????????????????????????? ??????????????-????????-????????i????. ???????????????? ??????????i ????i???? ?? ??i????i ??????
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??i??????i????i ????i???? ??i????i?? ?????????????????? ???????? Hsp70 ???? Hsp90 ?? ??????????i?? ????????????????i?? ???????????? ???? ???????????????????????? ??i?? ??i??????????????i??????i?? (3, 7, 10 i 14g) ?????????????? ?? ?????????????????????????? ??????????????-????????-????????i????. ???????????????? ??????????i ????i???? ?? ??i????i ??????
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Novartis Foundation symposium, 2008
Chaperokine is a term recently coined to better describe the dual role of extracellular heat shock protein as both chaperone and cytokine. The augmentation of intracellular Hsp72 expression has clearly been demonstrated to be cytoprotective; with the ability to activate anti-apoptotic and anti-inflammatory pathways, exerting inhibitory effects on cell ...
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Chaperokine is a term recently coined to better describe the dual role of extracellular heat shock protein as both chaperone and cytokine. The augmentation of intracellular Hsp72 expression has clearly been demonstrated to be cytoprotective; with the ability to activate anti-apoptotic and anti-inflammatory pathways, exerting inhibitory effects on cell ...
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Hsp70: A Cancer Target Inside and Outside the Cell.
Methods in molecular biology, 2018C. Boudesco +3 more
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