Results 291 to 300 of about 158,688 (339)

Heat Therapy: Targeting Health, Disease, and Disability

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey, Robert D. Hyldahl, Brendan W. Kaiser, Paige C. Geiger, John R. Halliwill, Christopher T. Minson   +5 more
wiley   +1 more source

Overcoming cancer drug resistance through small-molecule targeting of HSP90 and HSP70. [PDF]

Cancer Drug Resist
Cai RD, Lin MJ, Ye QM.
europepmc   +1 more source

Hypercapnia Effects on Lung Function

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
CO2 is a signaling molecule that disrupts alveolar fluid clearance and ion transport, impairs alveolar repair, and promotes mitochondrial and endoplasmic reticulum dysfunction. It suppresses innate immunity, host defense, and inflammation, while increasing airway contractility.
Seungseo Choi, Laura A. Dada, Jacob I. Sznajder   +2 more
wiley   +1 more source

In long-lasting cellular stress phases of melanoma cells, stress granules are dissolved by HSP70. [PDF]

Cell Mol Life Sci
Staebler S, Pieger K, Perl J, Stieglitz D, Thongmao A, Schneider N, Bosserhoff AK, Kuphal S.   +7 more
europepmc   +1 more source

The Phospholipid Bis(monoacylglycero)Phosphate Confers Antitumour Immunogenicity to Exosomes Secreted by Dendrogenin A, Which Activates Its Biosynthesis in Tumour Cells

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Dendrogenin A stimulates, via LXRβ, the expression and activity of enzymes responsible for the biosynthesis of the phospholipid BMP. BMP is a key determinant of the antitumour immunogenicity of exosomes secreted by DDA‐treated melanoma and triple‐negative breast cancer cells and enhances mouse survival and anti‐PD‐1 therapy in melanoma.
Julio Buñay, Michel Record, Philippe de Medina, Silia Ayadi, Laly Pucheu, Céline Colacios, Bruno Ségui, Marcus Höring, Gerhard Liebisch, Hélène Martin, Marc Poirot, Sandrine Silvente‐Poirot   +11 more
wiley   +1 more source

Cellulose-Encapsulated Magnetite Nanoparticles for Spiking of Tumor Cells Positive for the Membrane-Bound Hsp70. [PDF]

Int J Mol Sci
Dmitrieva A, Ryzhov V, Marchenko Y, Deriglazov V, Nikolaev B, Yakovleva L, Smirnov O, Matveev V, Yudintceva N, Spitsyna A, Varfolomeeva E, Combs SE, Konevega AL, Shevtsov M.   +13 more
europepmc   +1 more source

Tissue‐Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri, Erez Eitan, Kenneth W. Witwer, Diane B. Re, Andrea A. Baccarelli, Haotian Wu   +5 more
wiley   +1 more source

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis. [PDF]

Hemasphere
El Hoss S, Lizarralde-Iragorri MA, Maciel TT, Hermine O.   +3 more
europepmc   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Correction to "Homosalate Boosts the Release of Tumour-derived Extracellular Vesicles With Protection Against Anchorage-Loss Property". [PDF]

J Extracell Vesicles
europepmc   +1 more source