The addition of heat shock protein 70 to <i>in vitro</i> maturation medium improves the post-thaw quality of vitrified oocytes. [PDF]
Rimayanti R +11 more
europepmc +1 more source
Ageing C. elegans prioritises chronic protein stress protection over acute stress response by coordinating HSF‐1 activity. Decreased PBS‐7 binding in aged worms reduces HSF‐1 degradation, enhancing its ability to upregulate protective factors against accumulating protein aggregates while simultaneously suppressing its activation under acute heat shock.
Hongwei Wang +11 more
wiley +1 more source
A therapeutic multi-epitope protein vaccine targeting HPV16 E6 E7 elicits potent tumor regression and cytotoxic immune responses. [PDF]
Zhu L +9 more
europepmc +1 more source
Research Progress of Exosome‐Derived microRNA in Alcohol Use Disorders: A Critical Review
Exosome‐derived microRNAs represent stable and mechanistically active mediators of alcohol‐induced multi‐organ injury. This review summarizes how chronic alcohol exposure reshapes exosomal miRNA cargo across the liver, immune system, and brain, highlighting key miRNAs with diagnostic value and therapeutic potential.
Bo Zhang +4 more
wiley +1 more source
Metabolic functions for molecular chaperones and stress proteins in microcephaly. [PDF]
Morris MJ, Ng DCH.
europepmc +1 more source
Transcriptional outputs and condensates – formation and function
Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin +4 more
wiley +1 more source
Comment on: Low expression of HSP27 and HSP70 predicts poor prognosis in laryngeal squamous cell carcinoma. [PDF]
Topkan D, Somay E, Topkan E, Selek U.
europepmc +1 more source
Identification of HSP70 family and screening of drought resistance genes in sugar beet. [PDF]
He F, Sun Y, Li N, Zhang S, Li G.
europepmc +1 more source
Seasonality affects key physiological pathways in Pontastacus leptodactylus during an Aphanomyces astaci epidemic outbreak. [PDF]
Alvanou MV +5 more
europepmc +1 more source

