Results 101 to 110 of about 24,867 (223)

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu   +4 more
wiley   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

Brain Age Estimation on T2‐FLAIR Scans for Application to Multiple Sclerosis

open access: yesHuman Brain Mapping, Volume 47, Issue 5, 1 April 2026.
While the brain‐age paradigm has emerged as a promising biomarker of neurodegeneration in multiple sclerosis (MS), most available brain‐age prediction models are based on 3D‐T1w scans, which are not acquired in routine clinical practice. Leveraging a large multicentre collection of scans from healthy controls, we developed an accurate brain‐age ...
Jordan Colman   +46 more
wiley   +1 more source

Clinical validation of a DNA methylation biomarker associated with overall survival of relapsed ovarian cancer patients

open access: yesInternational Journal of Cancer, Volume 158, Issue 7, Page 1821-1835, 1 April 2026.
What's new? Most patients with ovarian cancer (OC) relapse after first‐line chemotherapy, and prognosis with second‐line treatment depends largely on the platinum‐free interval. However, reliable biomarkers to predict response to second‐line therapy remain lacking.
Muhammad Habiburrahman   +7 more
wiley   +1 more source

Continuing use of e‐cigarettes after stopping smoking and relapse: Secondary analysis of a large randomised controlled trial

open access: yesAddiction, Volume 121, Issue 4, Page 994-997, April 2026.
Abstract Background and aims Smokers quitting successfully with the help of e‐cigarettes often continue vaping. It is not known whether this promotes or prevents relapse back to smoking. This study aimed to determine whether use of e‐cigarettes after successful smoking cessation affects the probability of relapse later on.
Peter Hajek   +8 more
wiley   +1 more source

Short‐term efficacy of biologics in moderate‐to‐severe hidradenitis suppurativa: A systematic review and NMA

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
A meta‐analysis was conducted comparing the efficacy of biologics for the treatment of hidradenitis suppurativa (HS) for 12–16 weeks. Based on the SUCRA, bimekizumab was ranked the most efficacious treatment compared with secukinumab and adalimumab for all assessed efficacy outcomes, positioning it as the best treatment across biologic‐naïve and ...
Haley B. Naik   +9 more
wiley   +1 more source

Graft and Patient Survival After Liver Transplantation for Primary Sclerosing Cholangitis: A French National Cohort Study

open access: yesLiver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background A significant proportion of patients presenting a primary sclerosing cholangitis (PSC) will require liver transplantation (LT). The present study aimed to investigate graft loss and patient death in a large cohort of patients. Methods We conducted a nationwide multicenter retrospective study including all adult patients transplanted
Florian Veyre   +35 more
wiley   +1 more source

Distribution of Electrical Resistivity in Single Carbon Fiber Filaments and Its Correlation With Tensile Modulus

open access: yesAdvanced Engineering Materials, Volume 28, Issue 6, 18 March 2026.
A statistical framework is applied to quantify the distribution of electrical resistivity among individual filaments of two commercially available carbon fiber types. Correlations between filament resistivity, tensile modulus, and diameter are examined and complemented by TEM analysis to provide new insight into filament‐level variability relevant for ...
Nils Wieja   +9 more
wiley   +1 more source

Crossing borders: the need for empirical evidence of real-world evidence transportability in oncology

open access: yesJournal of Comparative Effectiveness Research
Plain language summary: What is this article about? This article discusses the challenges of using non local real-world evidence (RWE) in health technology assessments (HTA) when local data are unavailable, insufficient, or inappropriate.
Caitlin Clunie-O’Connor   +6 more
doaj   +1 more source

First LiDAR Observation of Quasi‐Periodic Structures in Mid‐Latitude E‐Region Meteoric Ca+ Layers

open access: yesGeophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract We report the first LiDAR observations of continuous quasi‐periodic (QP) metal density structures in mid‐latitude E‐region meteoric Ca+ layers using an all‐solid‐state LiDAR system in Beijing (40.4°N, 116.0°E). These QP Ca+ structures, with periods of 2–30 min and vertical wavelengths of ∼2–15 km, were primarily observed above 100 km.
Jixin Guo   +9 more
wiley   +1 more source

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