Results 161 to 170 of about 125,964 (294)

Identifying subjects at risk of liver cirrhosis via a range of thresholds for common fibrosis markers: A Welsh general population‐based cohort study

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 398-413, March 2026.
Abstract Background Liver disease is on the increase worldwide, with cirrhosis and liver cancer accounting for around 3.5% of all deaths. Objectives Investigate the prognostic utility of three non‐invasive liver fibrosis markers in the Welsh primary care population for identification of those at risk of cirrhosis or hepatocellular carcinoma (HCC ...
Trevor A. Hill   +3 more
wiley   +1 more source

Establishing a national HTA program for medical devices in Italy: Overhauling a fragmented system to ensure value and equal access to new medical technologies

open access: hybrid, 2021
Rosanna Tarricone   +10 more
openalex   +1 more source

Does the Dynamic Support Register Identify the Risk of Early Placement Breakdown in Adults With Intellectual Disabilities? Perceptions of Service Users, Carers and Professionals

open access: yesJournal of Policy and Practice in Intellectual Disabilities, Volume 23, Issue 1, March 2026.
ABSTRACT Placement breakdown is a common cause of avoidable admissions to intellectual disability inpatient services among people with intellectual disability. The Dynamic Support Register with intensive support function was introduced to help minimise these admissions.
Navakanth Rajulapati, Kathryn Berzins
wiley   +1 more source

Sertraline and Mirtazapine Versus Placebo in Subgroups of Depression in Dementia: Findings From the HTA-SADD Randomized Controlled Trial [PDF]

open access: hybrid, 2019
Marij Zuidersma   +4 more
openalex   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 218-241, February 2026.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian   +9 more
wiley   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo   +22 more
wiley   +1 more source

PNS179 HTA IMPLEMENTATION IN MIDDLE EAST AND NORTH AFRICA: COMPARISON OF CURRENT AND PREFERRED STATUS [PDF]

open access: bronze, 2019
Ahmad Nader Fasseeh   +12 more
openalex   +1 more source

Sentinel Lymph‐Node Biopsy Guided Neck Dissection Versus Elective Neck Dissection in the Management of Early‐Stage Oral Cancer—A Cost‐Utility Analysis

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Objectives This study aims to assess the incremental cost per quality‐adjusted‐life‐year (QALY) gained in treating patients with early oral squamous cell carcinoma (OSCC) using sentinel lymph node biopsy (SLNB) guided neck dissection. Methods A Markov model was created to simulate disease‐free survival, recurrence, and overall survival in a ...
Shivakumar Thiagarajan   +5 more
wiley   +1 more source

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