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Molecular biomarkers associated with ATLL and HAM progression in HTLV-1 infection: a systematic review. [PDF]

Rev Inst Med Trop Sao Paulo
Leite T, Abreu MES, Silva AAR, Sebastião RAS, Romão LA, Casseb J, Assone T, Leal FE, Mateos SOG.   +8 more
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Reflection About the Ancient Emergence of HTLV-2 Infection

AIDS Research and Human Retroviruses, 2022
During millions of years, viruses have emerged and reemerged, with imbalance of photogenicity and transmissivity overtime. This letter describes that sometimes the nomenclature is uncertain what may actually happen during retrovirus evolution nowadays.
Jorge Casseb, Luciano Rodrigo Lopes
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Hematologic hints of HTLV-2 in US blood donors

Blood, 2008
The HOST investigators have maintained a multiregional and longitudinal survey of donors infected with HTLV-I and HTLV-II for over 14 years. The survey has provided extremely valuable information regarding the long-term consequences of asymptomatic infection with HTLV-I or HTLV-II.[1][1],[2][2 ...
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Human Lymphotropic Viruses: HTLV-1 and HTLV-2

2016
Human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) and the more recently recognized HTLV-3 and HTLV-4 are human retroviruses of the genus Deltaretrovirus originally derived from closely related simian viruses. Proviral DNA is integrated in the host genome and propagated by lymphocytic division with only a minimal production of infectious
Roberta L. Bruhn, Renaud Mahieux, Edward L. Murphy   +2 more
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Molecular epidemiology of HTLV-2 infection among intravenous drug users in Spain

Journal of Clinical Virology, 2005
HTLV-2 infection is prevalent among intravenous drug users (IDUs), which often are coinfected with HIV-1. Two main subtypes, HTLV-2a and -2b, have been described among European IDUs, with a characteristically geographic distribution: IIa in northern Europe and IIb in the south.
Carlos, Toro, Berta, Rodés, Sylvina, Bassani, Victoria, Jiménez, Concepción, Tuset, María Teresa, Brugal, Luis, de la Fuente, Vincent, Soriano   +7 more
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Rétrovirus humains HTLV-1 et HTLV-2

EMC - Maladies infectieuses, 2004
Resume Human T cell leukemia/lymphoma virus type 1 (HTLV-1), premier retrovirus oncogene decouvert chez l'homme en 1980, possede, outre les genes gag, pol et env codant les proteines structurales et enzymatiques du virus, une region unique (nommee pX) codant les proteines regulatrices Tax et Rex.
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Prevalence and first detection of HTLV-2 in a pregnant woman in rural Brazil

Acta Tropica
Human T-lymphotropic virus (HTLV) is a retrovirus with two subtypes, HTLV-1 and HTLV-2. HTLV-1 is linked to severe diseases such as adult T-cell leukemia/lymphoma (ATLL) and HTLV-associated myelopathy, while HTLV-2 is considered less pathogenic but can cause fibromyalgia, hairy cell leukemia, and neurological disorders.
Gabriela Rodrigues de Aguiar Leal, Gabriel Galindo Cunha, Ana Eliza Vargas Eskinazi Sant’Anna, Artur Fernando Soares da Silva, Elisa de Almeida N. Azevedo, Clarice Neuenschwander Lins de Morais, José Humberto de Lima Melo, Maria Rosângela Cunha Duarte Côelho   +7 more
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NK cells constitute a major reservoir of HTLV‐2 infection in vivo

The FASEB Journal, 2008
HTLV‐2 is a deltaretrovirus, possibly associated with neurological manifestations. Initially believed to be restricted to CD8+ lymphocytes, the virus has been shown to infect also CD4+ T‐cells and B cells. Here we show for the first time that HTLV‐2 also infects NK cells in vivo .
Andre L A Oliveira, Allison Waters, Doris Schor, Ana Claudia Leite, Abelardo Araújo, William W Hall   +5 more
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Increased Risk of Developing Peripheral Neuropathy in Patients Coinfected With HIV-1 and HTLV-2

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2002
One thousand one hundred fifty-two HIV-1-positive patients were screened for HTLV-2 infection, and the AIDS-free coinfected individuals were consecutively included in a longitudinal study with the aim of investigating the role of HTLV-2 in the progression to AIDS and the development of specific neurologic diseases.
G. Zehender, C. Colasante, S. Santambrogio, C. De Maddalena, B. Massetto, B. Cavalli, G. Jacchetti, M. Fasan, F. Adorni, M. Osio, M. Moroni, M. Galli   +11 more
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Humane T-lymphotrope Viren HTLV-1, HTLV-2

2009
Die humanen T-lymphotropen Viren HTLV-1 und HTLV-2 reprasentieren die 2. Gruppe der beim Menschen vorkommenden exogenen Retroviren. Wahrend HIV-1 und HIV-2 zu den Lentiviren zahlen, gehoren HTLV-1 und HTLV-2 zum Genus Delta-Retrovirus. HTLV-1 wurde 1981 in T-Zell-Linien entdeckt, die von Patienten mit adulter T-Zell-Leukamie etabliert worden waren.
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