Results 51 to 60 of about 141,718 (249)

Prevalence of sexually transmitted infections among HIV-infected women in Brazil

Brazilian Journal of Infectious Diseases, 2012
This study aimed to evaluate the prevalence of sexually transmitted infections (STIs) and associated risk factors in HIV-infected pregnant women followed for prenatal care in Salvador, Bahia.
Ana Gabriela Álvares Travassos, Carlos Brites, Eduardo M. Netto, Sheyla de Almeida Fernandes, George W. Rutherford, Conceição Maria Queiroz   +5 more
doaj   +5 more sources

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. [PDF]

, 1987
Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity ...
Carson, DA, Kornbluth, RS, Richman, DD
core  

Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients

Brazilian Journal of Infectious Diseases
OBJECTIVE: To compare the clinical characteristics and outcomes of HIV-1-HTLV-1 coinfected patients, in Bahia, Brazil. METHODS: Retrospective, comparative study. RESULTS: Among a total of 123 consecutive HIV infected patients, 20 men (20.6%) and 6 women (
C Brites, F Goyanna, LG França, C Pedroso, EM Netto, S Adriano, J Sampaio, W Harrington Jr   +7 more
doaj   +1 more source

HTLV-1/-2 and HIV-1 Co-infections: Retroviral Interference On Host Immune Status

Frontiers in Microbiology, 2013
The human retroviruses HIV-1 and HTLV-1/HTLV-2 share similar routes of transmission but cause significantly different diseases. In this review we have outlined the immune mediated mechanisms by which HTLVs affect HIV-1 disease in co-infected hosts ...
Elisabetta ePilotti, Vittoria eBianchi, Andrea eDe Maria, Andrea eDe Maria, Andrea eDe Maria, Federica eBozzano, Federica eBozzano, Maria Grazia Romanelli, Umberto eBertazzoni, Claudio eCasoli   +9 more
doaj   +1 more source

Neurologic abnormalities in HTLV-I– and HTLV-II–infected individuals without overt myelopathy [PDF]

Neurology, 2009
Human T-lymphotropic virus (HTLV) type I is the causative agent of HTLV-associated myelopathy (HAM)/tropical spastic paraparesis, and a number of HAM cases with HTLV-II infection have also been reported. However, despite some reports, it is unclear whether HTLV-I or -II infection is associated with other neurologic manifestations.An analysis of medical
H H, Biswas, J W, Engstrom, Z, Kaidarova, G, Garratty, J W, Gibble, B H, Newman, J W, Smith, A, Ziman, J L, Fridey, R A, Sacher, E L, Murphy   +10 more
openaire   +2 more sources

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

Aquaporin-4 Antibodies Are Not Related to HTLV-1\ud Associated Myelopathy [PDF]

, 2012
Introduction: The seroprevalence of human T-cell leukemia virus type 1 (HTLV-1) is very high among Brazilians (,1:200).\ud HTLV-1 associated myelopathy or tropical spastic paraparesis (HAM/TSP) is the most common neurological complication of\ud HTLV-1 ...
Brandão, Carlos Otávio, Casseb, Jorge Simão do Rosário, Damasceno, Alfredo, Damasceno, Benito P., Farias, Alessandro S., Jarius, Sven, Longhini, Ana Leda F., Moraes, Adriel S., Oliveira, Augusto C. Penalva de, Santos, Leonilda M. B., von Gleh, Felipe, Wandinger, Klaus-Peter, Wildemann, Brigitte   +12 more
core   +2 more sources

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV‐1 genetic diversity in the two main ethnic populations

International Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.
What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy, Patricia Tortevoye, Balthazar Ntab, Gabriel Carles, Jean‐Pierre Droz, Pierre Couppié, Giovanni Begliomini, Jean‐Francois Carod, N'detodji‐Bill Wankpo, Karim Abdelmoumen, Philippe V. Afonso, Olivier Cassar, Antoine Talarmin, Olivier Hermine, Loïc Epelboin, Ambroise Marçais, Antoine Gessain   +16 more
wiley   +1 more source

Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection [PDF]

, 2008
Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is greater than that of men.
Minoru Tabata, Nobuoki Eshima, Shigeru Karukaya, Yasunori Higuchi   +3 more
core   +1 more source