Results 31 to 40 of about 48,838 (229)

Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases [PDF]

open access: yesLife, 2021
The human T-lymphotropic viruses (HTLVs) are causative agents of severe diseases including adult T-cell leukemia. Similar to human immunodeficiency viruses (HIVs), the viral protease (PR) plays a crucial role in the viral life-cycle via the processing of the viral polyproteins. Thus, it is a potential target of anti-retroviral therapies. In this study,
Norbert Kassay   +4 more
openaire   +3 more sources

HTLV-1 and HIV/HTLV-1 prevalence distribution by sex and age class.

open access: yes, 2022
The figure shows the overall prevalence of infection by age group and the prevalence of infection by sex: A) In the HIV-1/HTLV-1 coinfected population; B) In the general population at the same place.
Jeanne Sica (686072)   +10 more
core   +1 more source

HTLV-1 prevalence by age and gender in seven remote central Australian communities, 2014–18.

open access: yes, 2021
HTLV-1 prevalence by age and gender in seven remote central Australian communities, 2014–18.
Antoine Gessain (31917)   +7 more
core   +1 more source

HTLV-1 reads aligned to HTLV-1 sequences of the NCBI sequence data base.

open access: yes, 2019
HTLV-1 reads aligned to HTLV-1 sequences of the NCBI sequence data base.
Claudia Pommerenke (150761)   +3 more
core   +1 more source

Making Visible HTLV Infection in a Non-endemic Area of Argentina

open access: yesFrontiers in Medicine, 2022
In Argentina, the human T-cell lymphotropic virus type 1 (HTLV-1) infection has been documented mainly among blood banks with a prevalence of ~0.02–0.046% for Buenos Aires city, 0.8% for the northeast, and 1% for the northwest; both areas are considered ...
Federico R. Simioli   +7 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

HTLV-1 in Ophthalmology [PDF]

open access: yesFrontiers in Microbiology, 2020
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus described as a causative agent for human disease. In the field of ophthalmology, a close relationship between HTLV-1 infection and uveitis was identified through a series of clinical and laboratory studies in the late 1980s-1990s.
Koju Kamoi, Koju Kamoi, Koju Kamoi
openaire   +3 more sources

HTLV-1 proviral load of symptomatic patients.

open access: yes, 2019
HTLV-1 proviral load of symptomatic patients.
Ariel Fridman (7961834)   +11 more
core   +1 more source

Synergistic effects of HDAC inhibitor tucidinostat and ENT inhibitor dipyridamole in T-cell malignancies

open access: yesScientific Reports
Achieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically regulating tumor suppressor gene expression
Jiazhou Li   +10 more
doaj   +1 more source

Human T-lymphotropic virus infection and population characteristics of blood donors in Hainan

open access: yesZhongguo shuxue zazhi
[Objective] To investigate the prevalence of human T-lymphotropic virus (HTLV) infection among voluntary blood donors and provide reference for the development of blood safety screening strategy in Hainan Province.
HUANG Yiqing   +3 more
doaj   +1 more source

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