Results 31 to 40 of about 35,270 (186)

HTLV-1 encephalitis [PDF]

open access: yesPractical Neurology, 2021
A 53-year-old woman developed subacute onset of upper limb weakness, sensory loss and cerebellar dysfunction. She was known to have human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy. MR scan of the brain showed extensive T2 hyperintensity within the deep and subcortical white matter, with punctate contrast enhancement.
King-Robson, J   +4 more
openaire   +3 more sources

High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2013
BackgroundHuman T-cell lymphotropic virus type 1 (HTLV-1) infection can increase the risk of developing skin disorders. This study evaluated the correlation between HTLV-1 proviral load and CD4(+) and CD8(+) T cells count among HTLV-1 infected ...
Renata Okajima   +4 more
doaj   +1 more source

HAM/TSP and major depression: the role of age

open access: yesBrazilian Journal of Infectious Diseases, 2015
Objective: To investigate the role of demographic variables in the relationship between the presence of HAM/TSP and current major depression. Methods: It is a cross-sectional study of 108 HTLV-1 infected patients (47 with TSP/HAM) resident of Salvador ...
Ney Boa-Sorte   +4 more
doaj   +1 more source

Revisiting Keratoconjunctivitis sicca associated with Human T-Cell Lymphotropic Virus Type 1: prevalence, clinical aspects and proviral load

open access: yesBrazilian Journal of Infectious Diseases, 2019
Background: The prevalence of keratoconjunctivitis sicca (KCS) associated with Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) (HTLV-1/KCS) has been estimated at around 37%, but its clinical manifestations are poorly described.
Regina Helena Rathsam-Pinheiro   +6 more
doaj   +1 more source

Sex, Age, and Risk Group Variations among Individuals Infected with HIV, HTLV-1, and HTLV-2: Review of Data Records (1983–2017) from a Public Health Laboratory in São Paulo, Brazil

open access: yesSexes, 2023
The inaugural AIDS Program in Brazil was established in São Paulo in 1983, with the Instituto Adolfo Lutz appointed for laboratory assistance. Subsequently, research on HIV infections and HIV/HTLV (HIV/HTLV-1 and HIV/HTLV-2) co-infections was conducted ...
Adele Caterino-de-Araujo
doaj   +1 more source

HTLV-1 in Ophthalmology [PDF]

open access: yesFrontiers in Microbiology, 2020
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus described as a causative agent for human disease. In the field of ophthalmology, a close relationship between HTLV-1 infection and uveitis was identified through a series of clinical and laboratory studies in the late 1980s-1990s.
Koju Kamoi, Koju Kamoi, Koju Kamoi
openaire   +3 more sources

طراحی مهارکننده‌های جدید پپتیدی با گروههای عاملی بر پایه بنزن برای پروتئاز ویروس HTLV-1 با روشهای محاسباتی [PDF]

open access: yesمجله دانشگاه علوم پزشکی سبزوار, 1970
زمینه و هدف : ویروس htlv-1 جز خانواده رتروویروس‌ها می‌باشد ، این ویروس در انسان باعث ایجاد بیماری‌هایی نظیر لوسمی T-Cell بزرگسالان (ATL )، HAM/TSP و ... می‌گردد .
جواد ملکی   +3 more
doaj  

PREVALENCE OF HIV-1/HTLV-1 CO-INFECTION AND BEHAVIORAL RISK AMONG PEOPLE LIVING WITH HIV IN BELO HORIZONTE, BRAZIL

open access: yesRevista de Salud Pública, 2023
Objective: To analyze the prevalence of HIV-1 and HTLV-1 co-infection and risk behavioral for sexually transmitted infections (STIs) and the quality of life among people living with HIV-1 (PL-HIV-1).
Poliane Cristina Vertêlo   +6 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Synergistic effects of HDAC inhibitor tucidinostat and ENT inhibitor dipyridamole in T-cell malignancies

open access: yesScientific Reports
Achieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically regulating tumor suppressor gene expression
Jiazhou Li   +10 more
doaj   +1 more source

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