Results 61 to 70 of about 35,270 (186)

Cost-effectiveness of human T-cell leukemia virus type 1 (HTLV-1) antenatal screening for prevention of mother-to-child transmission.

PLoS Neglected Tropical Diseases, 2023
BackgroundHuman T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM/TSP) with a poor prognosis.
Akiko Kowada
doaj   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

European Journal of Haematology, Volume 117, Issue 2, Page 481-491, August 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida, Seigo Tateo, Masahiro Wakao, Hiroyuki Shinchi, Hayate Sawayama, Akira Fukumoto, Makoto Yoshimitsu, Yasuo Suda   +7 more
wiley   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 795-806, August 2026.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

The m.14484T>C MT‐ND6 Mutation Presenting with a Hereditary Spastic‐Paraparesis Phenotype

Movement Disorders Clinical Practice, EarlyView.
Gabriel Amorelli, Christelle Nilles, Gerald Pfeffer, Matthew Joel, Davide Martino   +4 more
wiley   +1 more source

Trends in Mortality After the Roll‐Out of Directly Acting Antivirals for Hepatitis C in England Using Linked Surveillance Data

Journal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT Directly acting antivirals (DAAs) revolutionised hepatitis C virus (HCV) treatment, offering higher cure rates. We aimed to quantify life expectancy (LE) differences between treated and untreated individuals diagnosed with HCV and assess the contributions of age and causes of death to these differences.
David Etoori, Ruth Simmons, Annabel Powell, Monica Desai, Paul Trembling, Caroline Sabin, William Rosenberg   +6 more
wiley   +1 more source

Anemia as a Public Health Issue in Mashhad, Iran: Evidence from the First Population-Based Study

Acta Medica Iranica, 2015
Anemia is one of the main conditions that impose an adverse impact on the socioeconomic state of any country; however, evidence on the prevalence of anemia is scant in Northeastern Iran.
Iman Eftekharzadeh-Mashhadi, Mohammad Reza Hedayati-Moghaddam, Farhad Fathimoghadam, Hamid Reza Bidkhori, Seyed Khosro Shamsian   +4 more
doaj  

Prevalence of Human T-lymphotropic virus type 1 and 2 among blood donors in Manaus, Amazonas State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2017
Introduction: Human T-lymphotropic virus type 1 and 2 (HTLV-1/2) is endemic in Brazil, but few studies have investigated the seroprevalence of HTLV and its subtypes among blood donors in the capital city Manaus, Amazonas State, Brazil.
Márcia Poinho EncarnaçÃo de Morais, Cynara Melo Gato, Lucinei Alves Maciel, Pritesh Lalwani, Cristóvão Alves Costa, Jaila Dias Borges Lalwani   +5 more
doaj   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

Prevalence of Hepatitis C Virus Infection in General Population of Mashhad, Northeastern Iran

Iranian Journal of Public Health, 2017
Background: Hepatitis C Virus (HCV) infection is one of the major blood-borne infections worldwide. HCV carriers may develop chronic hepatitis leading to liver cirrhosis and hepatocellular carcinoma (HCC).
Sanaz AHMADI GHEZELDASHT, Mohammad Reza HEDAYATI-MOGHADDAM, Khosro SHAMSIAN, Farhad FATHIMOGHADAM, Hamid Reza BIDKHORI, Seyed Abdolrahim REZAEE   +5 more
doaj  

Molecular and Phylogenetic Characterization of HTLV‐1 Infection in Patients With Hematological Malignancies in the State of Pará, Northern Brazil

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Human T‐lymphotropic viruses 1 and 2 (HTLV‐1 and HTLV‐2) were first isolated from patients with hematological malignancies. This study was the first to investigate the frequency of HTLV‐1 and its molecular diversity among patients with hematolymphoid cancers who were treated at a leading reference hospital in Pará, northern Brazil.
Gabriel dos Santos Pereira Neto, Ana Vilhena Alves, Bruno José Sarmento Botelho, Andrio Silva da Silva, Debora Monteiro Carneiro, Rommel Mario Rodriguez Burbano, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Izaura Maria Vieira Cayres Vallinoto   +8 more
wiley   +1 more source