Results 21 to 30 of about 37,531 (138)

PREVALENCE OF HIV-1/HTLV-1 CO-INFECTION AND BEHAVIORAL RISK AMONG PEOPLE LIVING WITH HIV IN BELO HORIZONTE, BRAZIL

Revista de Salud Pública, 2023
Objective: To analyze the prevalence of HIV-1 and HTLV-1 co-infection and risk behavioral for sexually transmitted infections (STIs) and the quality of life among people living with HIV-1 (PL-HIV-1).
Poliane Cristina Vertêlo, Alexandre Braga Miranda, Ludimila Labanca, Ana Lúcia Borges-Starling, Cláudio Daniel Cerdeira, Carlos Felipe Nogueira, Denise Utsch Gonçalves   +6 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Synergistic effects of HDAC inhibitor tucidinostat and ENT inhibitor dipyridamole in T-cell malignancies

Scientific Reports
Achieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically regulating tumor suppressor gene expression
Jiazhou Li, Ahmed E. Goda, Daniel Enriquez-Vera, Shuhei Fujii, Satomi Harazono, Jhajaira M. Araujo, Nao Nishikoba, Sophia Velarde, Atakan Zeki Namli, Alvaro De Jesus Huamani Ortiz, Shingo Nakahata   +10 more
doaj   +1 more source

Human T-lymphotropic virus infection and population characteristics of blood donors in Hainan

Zhongguo shuxue zazhi
[Objective] To investigate the prevalence of human T-lymphotropic virus (HTLV) infection among voluntary blood donors and provide reference for the development of blood safety screening strategy in Hainan Province.
HUANG Yiqing, HAN Hui, ZHANG Jiongjiong, ZHANG Yongli   +3 more
doaj   +1 more source

Leucemia/Linfoma T Seronegativo

Revista Digital de Postgrado
La leucemia/linfoma de células T del adulto (ATLL) es una neoplasia linfoproliferativa agresiva de linfocitos T CD4+/CD25+, asociada en más del 95 % de los casos a infección por HTLV-1, cuya seropositividad constituye un criterio diagnóstico esencial ...
Ligia Ramírez, Raul Strocchia, Zaidith Zerpa, Edgar García, Analiesse Marchan, Lucymar Escalona, Fernando Carrera, Sonia De Abreu   +7 more
doaj   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

Caracterização molecular do HTLV-1 em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-1 em Belém, Pará Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará

Revista da Sociedade Brasileira de Medicina Tropical, 2006
O presente estudo avaliou a ocorrência da infecção pelo HTLV-1 e seus subtipos em amostras de sangue de pacientes com diagnóstico clínico de paraparesia espástica tropical/mielopatia associada ao Htlv-1.
Lucinda A. Souza, Ivina G.L. Lopes, Eduardo Leitão Maia, Vânia N. Azevedo, Luiz Fernando A. Machado, Marluísa O.G. Ishak, Ricardo Ishak, Antonio Carlos R. Vallinoto   +7 more
doaj   +1 more source

Flow cytometric assessment of T‐cell receptor β‐chain constant region 1/2 skewing as a surrogate marker for clonality in human T‐cell leukaemia virus type‐1–infected cells

British Journal of Haematology, EarlyView.
Summary Estimating T‐cell clonality within human T‐cell leukaemia virus type 1 (HTLV‐1)–infected cell populations may aid risk assessment and diagnosis of adult T‐cell leukaemia/lymphoma (ATL). However, direct assessment of HTLV‐1 integration‐site clonality requires genetic analyses that are costly and labour‐intensive.
Koji Jimbo, Aileen G. Rowan, Momoko Usui, Kako Suzuki, Makoto Yamagishi, Junya Makiyama, Lucy B. M. Cook, Yoshihisa Yamano, Kaoru Uchimaru, Yasuhito Nannya, Shigeo Fuji   +10 more
wiley   +1 more source

Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4

Retrovirology, 2009
Background Human T-lymphotropic virus type 4 (HTLV-4) is a new deltaretrovirus recently identified in a primate hunter in Cameroon. Limited sequence analysis previously showed that HTLV-4 may be distinct from HTLV-1, HTLV-2, and HTLV-3, and their simian ...
Wolfe Nathan D, Pryor Kendle N, Marriott Susan J, Katzourakis Aris, Gray Rebecca R, Jia Hongwei, Qari Shoukat H, Salemi Marco, Switzer William M, Burke Donald S, Folks Thomas M, Heneine Walid   +11 more
doaj   +1 more source

Distinct Clinical Features of Multiple Myeloma With t(11;14): A Post Hoc Analysis of JSH‐MM‐15 Study

Cancer Science, EarlyView.
t(11;14)‐positive MM is a clinically distinct subgroup characterized by intermediate prognostic risk, modest response depth, and treatment‐dependent outcomes. ABSTRACT t(11;14) (q13;q32) occurs in approximately 15%–25% of multiple myeloma (MM) cases and has traditionally been regarded as a standard cytogenetic risk factor.
Taku Tsukamoto, Yuji Shimura, Shinsuke Mizutani, Takahiro Fujino, Haruya Okamoto, Mitsuhiro Itagaki, Hiroshi Handa, Takayuki Shimizu, Morio Sawamura, Tadao Ishida, Satoru Kosugi, Shuichi Ota, Makoto Yoshimitsu, Yutaka Shimazu, Isamu Sugiura, Hirohiko Shibayama, Shin‐ichi Fuchida, Hiroyuki Takamatsu, Akiko M. Saito, Hitoshi Kiyoi, Koichi Akashi, Itaru Matsumura, Akifumi Takaori‐Kondo, Junya Kuroda, Shinsuke Iida   +24 more
wiley   +1 more source