Results 61 to 70 of about 45,904 (239)

Distribution of adult T‐cell leukaemia/lymphoma subtypes and survival outcomes across geographical regions: An international retrospective cohort study

British Journal of Haematology, EarlyView.
Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel, Atae Utsunomiya, Maki Otsuka, Masaharu Miyahara, Kenji Ishitsuka, Yasushi Takamatsu, Junji Suzumiya, Kazuo Tamura, Jule F. Vasquez, Daniel Enriquez‐Vera, Brady E. Beltran, Denisse Castro, Thanya Runciman, Henry Idrobo, Elizabeth Arrieta, Oriana Arias, Eduardo Gotuzzo, Gabriela Garrido‐Pinzás, Victor Rivera, Daniel La Rosa, Camila Peña, Lorena Fiad, Juan C. Ramos, Jose Sandoval‐Sus, Alejandro Sica, Britney N. Bell, Lucy B. Cook, Veronica Leataud, Eliana C. M. Miranda, Carlos Chiattone, Hiroo Katsuya, Luis Malpica   +31 more
wiley   +1 more source

HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.

, 2018
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection ...
Maria Makuwa (131491), Guillaume Besson (313049), Melanie Caron (2558596), Eric Leroy (264004), Dieudonne Nkoghe (3404600), Cindy Padilla (201518), Mirdad Kazanji (136517)   +6 more
core   +1 more source

HTLV infection in persons with sexually transmitted diseases in Spain [PDF]

, 2023
Background: HTLV-1 infection is a neglected disease, despite estimates of 10 million people infected worldwide and producing life-threatening illnesses in 10% of carriers. Sexual transmission is the main route of contagion.
Spanish HTLV Network, Ayerdi, Oskar, Aguilera Guirao, Antonio, Baza, Begoña, Pintos, Ilduara, Díaz de Santiago, Alberto, Soriano, Vicente, Montiel, Natalia, Mendoza, Carmen de, Aguilera, Antonio, Benito, Rafael, Ortega, Diego, de Mendoza, Carmen   +12 more
core   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida, Seigo Tateo, Masahiro Wakao, Hiroyuki Shinchi, Hayate Sawayama, Akira Fukumoto, Makoto Yoshimitsu, Yasuo Suda   +7 more
wiley   +1 more source

UK Infected Blood Inquiry–An Historical Appraisal

Haemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source

Epidemic Patterns of Hepatitis Type B Virus (HBV) and Human T Lymphotropic Virus Type I (HTLV-I) in Two ATL-Endemic Islands in Kyushu, Japan [PDF]

, 1991
1991-03To evaluate the relationships between human T lymphotropic virus type I (HTLV-I) and hepatitis virus type B (HBV) infections, we compared both individual and geographical distributions of carriers of HTLV-I and HBV, and antibody positives to HBV ...
KINOSHITA, KEN-ICHIRO, TACHIBANA, KAZUNORI, SHIRAHAMA, SATOSHI, NAGATOMO, MASAZUMI, ITO, SHIN-ICHIRO, TAJIMA, KAZUO   +5 more
core   +1 more source

Trends in the prevalence and distribution of HTLV-1 and HTLV-2 infections in Spain

Virology Journal, 2012
Background Although most HTLV infections in Spain have been found in native intravenous drug users carrying HTLV-2, the large immigration flows from Latin America and Sub-Saharan Africa in recent years may have changed the prevalence and distribution of ...
Treviño Ana, Aguilera Antonio, Caballero Estrella, Benito Rafael, Parra Patricia, Eiros Jose M, Hernandez Araceli, Calderón Enrique, Rodríguez Manuel, Torres Alvaro, García Juan, Ramos Jose, Roc Lourdes, Marcaida Goitzane, Rodríguez Carmen, Trigo Matilde, Gomez Cesar, de Lejarazu Raul, de Mendoza Carmen, Soriano Vincent   +19 more
doaj   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex-1

, 2011
Copyright information:Taken from "HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex"http://www.retrovirology.com/content/4/1/35Retrovirology 2007;4():35-35.Published online 29 May 2007PMCID:PMC1894815.
Randall Merling (75706), Chou-Zen Giam (75711), Sohee Hong (75708), Meihong Liu (75709), Yu-Liang Kuo (75710), Ling Zhang (18071), Chunhua Chen (75707)   +6 more
core   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source