Results 41 to 50 of about 8,869 (179)
MDM2 negatively regulates the human telomerase RNA gene promoter
BMC Cancer, 2005 Background We have previously demonstrated that NF-Y and Sp1 interact with the human telomerase RNA (hTR) promoter and play a central role in its regulation.
Keith W Nicol +3 more
doaj +1 more source
Telomerase contributes to fludarabine resistance in primary human leukemic lymphocytes. [PDF]
PLoS ONE, 2013 We report that Imetelstat, a telomerase inhibitor that binds to the RNA component of telomerase (hTR), can sensitize primary CLL lymphocytes to fludarabine in vitro.
May Shawi +9 more
doaj +1 more source
Transformation of the Agrarian Landscape and Hope in the Central Kalimantan Peatlands
Asia Pacific Viewpoint, EarlyView.ABSTRACT In Kalimantan, Indonesian Borneo, agrarian state programs and corporate strategies seek to transform indigenous Ngaju Dayak into sedentary farmers. Focusing on the notion of transformation, the paper traces whether and how rural people can engage in struggles against structural injustices.
Anu Lounela
wiley +1 more source
Revista Brasileira de Fruticultura, 2008 Visando a evitar os efeitos da poliembrionia, os quais dificultam a distinção entre indivíduos híbridos e aqueles de origem materna (nucelares). O Programa de Melhoramento Genético de Citros da Embrapa Mandioca e Fruticultura Tropical selecionou híbridos
Walter dos Santos Soares Filho +5 more
doaj +1 more source
, 2021 Im KONDE-Projekt, das aus Hochschulraumstrukturmitteln finanziert wird, beschäftigten sich sieben universitäre Partner und drei weitere Einrichtungen aus unterschiedlichen Blickwinkeln mit theoretischen und praktischen Aspekten der Digitalen Edition. Ein Outcome des Projektes stellt das Weißbuch dar, welches über 200 Artikel zum Thema Digitale Edition ...
openaire +1 more source
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Energetyka jądrowa i radioanalityka
Energetyka Rozproszona.plArtykuł przedstawia wieloaspektowe podejście do wykorzystania radionuklidów w kontekście ochrony środowiska i energetyki jądrowej oraz zasady przygotowania i prawidłowego użytkowania przyrządów dozymetrycznych stosowanych w ochronie radiologicznej ...
Katarzyna Szarłowicz +12 more
doaj +1 more source
Fermentation quality of herbal tea residue and its application in fattening cattle under heat stress
BMC Veterinary Research, 2021 Background Herbal tea residue (HTR) is generally considered to be the waste of herbal tea beverage production while it still retains rich nutrients and active substances.
Xiaona Zhuang +8 more
doaj +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, EarlyView.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
British Journal of Pharmacology, EarlyView.Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
wiley +1 more source