Results 121 to 130 of about 29,142 (240)

Multi-Omics Epigenetic Landscape Unveils Regulatory Mechanisms Underlying Heterosis in Sheep Muscle Development

Animals
Hybridization effectively enhances breeding efficiency and significantly boosts sheep productivity. However, the epigenetic mechanisms underlying the superior production performance of crossbreds remain largely elusive.
Jiangbo Cheng, Dan Xu, Huibin Tian, Xiaoxue Zhang, Liming Zhao, Runan Zhang, Jianlin Wang, Jinyu Xiao, Fadi Li, Weimin Wang, Deyin Zhang   +10 more
doaj   +1 more source

Genetic Diversity, Selection Signatures, and Genome-Wide Association Study Identify Candidate Genes Related to Litter Size in Hu Sheep

Hu sheep is a renowned prolific local sheep breed in China, widely distributed across the country due to its excellent reproductive performance. Deciphering the molecular mechanisms underlying the high fecundity of Hu sheep is crucial for improving the ...
Peifu Yang, Jingjing Bao, Jinke Xiong, Jupeng Huang, Mingyu Shang, Li Zhang   +5 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis

International Journal of Cancer, Volume 159, Issue 3, Page 782-796, 1 August 2026.
Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos, William P. Cawthorn, Joana Marinho‐Dias, Sofia Ramalheira, Susana Roncon, Dulcineia Pereira, Teresa Ribeiro, Carla Rodrigues, Mário Mariz, Ana Miranda, Helena Brízido, Manuel Bicho, Pedro Medeiros, Ana Carneiro, Fernanda Trigo, Pingzhao Hu, Flávia Pereira, Hugo Duarte, Calum D. Gray, Tom Macgillivray, Alan G. Ramsay, Maria J. Oliveira, Ricardo Ribeiro   +22 more
wiley   +1 more source

Effect of xylooligosaccharides to the diet on growth performance， nutrient apparent digestibility， immune function and rumen fermentation parameters of finishing Hu sheep

Siliao yanjiu, 2023
The study was to investigate the effect of different levels of dietary xylooligosaccharides on growth performance, immune function, nutrient apparent digestibility and ruminal fermentation parameters of finishing Hu sheep.
WANG Jian-jun, DONG Wei, ZHANG Jin-xue, FANG Yu-peng   +3 more
doaj  

Genetic Diversity and Selection Signal Analysis of Hu Sheep Based on SNP50K BeadChip

This research is designed to examine the genetic diversity and kinship among Hu sheep, as well as to discover genes associated with crucial economic traits.
Juanjuan Song, Dengpan Li, Keyan Ma, Taotao Li, Youji Ma   +4 more
core   +1 more source

Postprandial Glucagon Action in the Human Brain

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5926-5938, July 2026.
ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner, Stephanie Kullmann, Julia Hummel, Katsiaryna Prystupa, Elena Hosenfeld, Ralf Veit, Andreas L. Birkenfeld, Hans‐Ulrich Häring, Hubert Preissl, Andreas Fritsche, Andreas Peter, Martin Heni   +11 more
wiley   +1 more source

The epigenetic mechanisms of adaption to the hot and humid climate in Hu sheep (Ovis aries)

Physiological Reports
Hu sheep is characterized by its excellent fecundity and high adaptability to various ecological environments. To reveal the molecular basis involved in Hu sheep, we first examined the 10 index of neuroendocrine and metabolism in blood in Hu sheep during
Hangxing Ren, Jing Jiang, Jie Li, Xiaoyan Sun, Cancan Chen, Liangjia Liu, Shipeng Lv, Minghao Qu, Yuxue Fan, Peng Zhou, Gaofu Wang   +10 more
doaj   +1 more source

HaloTag Fusion Enables Dynamic Analysis of Prion Protein Biosynthesis, Turnover, and Misfolding

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Prion protein (PrP) misfolding underlies fatal neurodegenerative diseases. We developed a HaloTag‐based PrP fusion enabling spatiotemporal labeling of distinct PrP populations in living cells. This system recapitulates native PrP biology, reveals early misfolding events in disease‐associated mutants, and allows mechanistic interrogation of PrP‐lowering
Antonio Masone, Eleonora Busani, Roberto Chiesa   +2 more
wiley   +1 more source

ASIP Variants in Livestock: It's Not Black and White

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Fur and feather pigmentation play an important role in the survival and reproduction of many species, as well as in selective breeding and agriculture. The synthesis of pigment molecules, eumelanin and pheomelanin, is partially regulated by the agouti signalling protein (ASIP) encoded by the ASIP gene.
Isabella M. Brown, Kylie A. Munyard
wiley   +1 more source