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Inhibitory effect of SMAD2 on myogenesis in heat-stressed Hu sheep myoblasts

open access: yesJournal of Thermal Biology
Heat stress can cause muscle damage and affect myogenesis. Myogenesis is a complicated process modulated by numerous genes. While SMAD2 has been implicated in various biological processes, its specific role in the myogenesis of heat-stressed Hu sheep myoblasts remains unclear.
Jiawei Lu, Yilan Liu, Huixia Li
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Transcriptomics and metabolomics reveal improved performance of Hu sheep on hybridization with Southdown sheep

Food Research International, 2023
Consumers are increasingly demanding high-quality mutton. Cross breeding can improve meat quality and is widely used in sheep breeding. However, little is known about the molecular mechanism of cross breeding sheep meat quality. In this study, male Southdown and female Hu sheep were hybridized. The slaughter performance and longissimus dorsi quality of
Lingying, Kong   +6 more
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Relationship between rumen microbial differences and traits among Hu sheep, Tan sheep, and Dorper sheep

Journal of Animal Science, 2022
Abstract Rumen microbes play an important role in the growth and development of ruminants. Differences in variety will affect the rumen community structure. The three excellent sheep breeds were selected for this study (Hu sheep, Tan sheep, and Dorper sheep) have different uses and origins. The sheep were raised on the same diet to 180 d
Jiangbo Cheng   +20 more
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Integrative analysis of transcriptomics and proteomics of longissimus thoracis of the Hu sheep compared with the Dorper sheep

Meat Science, 2022
Meat quality is becoming more important for sheep breeding programs. Meat quality is a complex trait affected by genetic and environmental factors. In the present study, an integrative analysis of the longissimus thoracis tissue transcriptome and proteome was conducted to identify genes, proteins, and pathways related to meat quality in sheep.
Liming, Zhao   +14 more
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Comparative proteomics reveals genetic mechanisms of body weight in Hu sheep and Dorper sheep

Journal of Proteomics, 2022
Body weight (BW) is a critical economic trait for meat production in sheep, and it is a complex trait affected by numerous elements. The aim of this study was to investigate the genetic mechanisms of sheep BW by a label-free proteomics approach. The result showed, a total of 27, 14, 61, and 65 differentially abundant proteins (DAPs) were identified in ...
Liming, Zhao   +14 more
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SMAD2 regulates testicular development and testosterone synthesis in Hu sheep

Theriogenology, 2021
The SMAD protein family plays crucial roles in reproduction as a downstream target genes of the TGFβ signaling pathway. Many studies have focused on the expression change exploration of SMADs during testicular development and investigation of SMAD2 in hormone synthesis regulation.
Hua, Yang   +4 more
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Effect of Thawing Rates and Antioxidants on Semen Cryopreservation in Hu Sheep

Biopreservation and Biobanking, 2021
Hu sheep is a valuable sheep breed in China, and semen cryopreservation of Hu sheep is important for sustainable development of the agri-food industry. This study aimed to evaluate the effect of thawing rate and antioxidants (procyanidins [PC] and mitoquinone [MitoQ]) on the quality and antioxidant enzyme activity of post-thaw sperm in Hu sheep.
Caifeng, Wu   +5 more
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Three novel MC4R SNPs associated with growth traits in Hu sheep and East Friesian×Hu crossbred sheep

Small Ruminant Research, 2015
Abstract The melanocortin-4 receptor (MC4R) is a G-protein coupled receptor superfamily member, which has been implicated in regulating food intake, energy balance and body weight in mammals. Though the mutations of MC4R have been identified as genetic markers for growth traits in many livestock species, little is known about sheep MC4R gene.
Yalei Wang   +8 more
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Analysis of genetic co-adaptability of structural loci in Hu sheep

HEREDITAS, 2007
Using the method of multiloci electrophoresis, genetic co-adaptability of Hu Sheep was analyzed according to allele frequencies in 14 structural loci. The results showed that no co-adaptability existed in the dominance-dominance model, while co-adaptability was observed in X-p-Cat combination locus of dominance-codominance model and in Po-CA, Po-Cat ...
Rong-Qing, Geng   +6 more
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Reproductive characteristics of Chinese Hu sheep

Animal Reproduction Science, 1996
Abstract The reproductive characteristics of Chinese Hu sheep are reviewed. Male and female lambs reached puberty at a mean age of 120 days and 180 days, respectively, with an average body weight of 18.54 ± 1.48 kg ( n = 31) and 22.75 ± 1.98 kg ( n = 24). Adult male and female sheep reproduced throughout the year. On average, ewes lambed 1.65 times
openaire   +1 more source

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