Candidate SNP markers of changes in the expression levels of the human SCN9A gene as a hub gene for pain generation, perception, response and anesthesia. [PDF]
Vavilovskii Zhurnal Genet SelektsiiDotsenko PA +8 more
europepmc +1 more source
Deciphering infected cell types, hub gene networks and cell-cell communication in infectious bronchitis virus via single-cell RNA sequencing. [PDF]
PLoS PathogLiukang C +6 more
europepmc +1 more source
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Association analysis of hepatocellular carcinoma‐related hub proteins and hub genes
PROTEOMICS – Clinical Applications, 2023AbstractPurposeHepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The occurrence and development of HCC are closely related to epigenetic modifications. Epigenetic modifications can regulate gene expression and related functions through DNA methylation.
Xinhong Zhang +3 more
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RANKING DIFFERENTIAL HUBS IN GENE CO-EXPRESSION NETWORKS
Journal of Bioinformatics and Computational Biology, 2012Identifying the genes that change their expressions between two conditions (such as normal versus cancer) is a crucial task that can help in understanding the causes of diseases. Differential networking has emerged as a powerful approach to detect the changes in network structures and to identify the differentially connected genes among two networks ...
Omar, Odibat, Chandan K, Reddy
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Hub Genes Identification in Brain Cancer with Gene Expression Data
2020 20th International Conference on Advances in ICT for Emerging Regions (ICTer), 2020Central nervous system (CNS) cancers are one of the leading cancer types in the world. Analysing gene hubs involved in CNS cancer is important for predicting therapies. We have used gene expression data from one of the common brain cancer type (Pheochromocytoma /paraganglioma (PCPG)) for hub gene identification.
S. P. B. M Senadheera, A. R. Weerasinghe
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Weighted gene co-expression network analysis for hub genes in colorectal cancer
Pharmacological Reports, 2023This study is designed to explore hub genes participating in colorectal cancer (CRC) development through weighted gene co-expression network analysis (WGCNA).Expression profiles of CRC and normal samples were retrieved from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA), and were subjected to WGCNA to filter differentially ...
Zheng Xu, Jianing Wang, Guosheng Wang
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Spatial organization of gene expression: the active chromatin hub
Chromosome Research, 2003Developmental and tissue-specific expression of higher eukaryotic genes involves activation of transcription at the appropriate time and place and keeping it silent otherwise. Unlike housekeeping genes, tissue-specific genes generally do not cluster on the chromosomes.
de Laat, WL (Wouter), Grosveld, Frank
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Predicting Hub Genes Associated with Cervical Cancer through Gene Co-Expression Networks
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2016Cervical cancer is the third most common malignancy in women worldwide. It remains a leading cause of cancer-related death for women in developing countries. In order to contribute to the treatment of the cervical cancer, in our work, we try to find a few key genes resulting in the cervical cancer.
Su-Ping, Deng +2 more
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Identification of Potential Hub Genes in Alopecia Areata
Experimental DermatologyABSTRACT Alopecia areata (AA) is an immune‐mediated chronic alopecia disease, but its specific pathogenesis is unclear. Gene expression data for AA patients (AAs) and healthy controls (HCs) were retrieved from the GEO database, and the differentially expressed genes (DEGs) between AAs and HCs were identified.
Runqiu Liu +7 more
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