Results 41 to 50 of about 7,224,110 (273)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Conversational Agents, Humorous Act Construction, and Social Intelligence [PDF]

open access: yes, 2005
Humans use humour to ease communication problems in human-human interaction and \ud in a similar way humour can be used to solve communication problems that arise\ud with human-computer interaction.
Nijholt, Anton
core   +1 more source

Human computer interaction using hand gesture. [PDF]

open access: yes, 2008
Hand gesture is a very natural form of human interaction and can be used effectively in human computer interaction (HCI). This project involves the design and implementation of a HCI using a small hand-worn wireless module with a 3-axis accelerometer as ...
Nguyen, HT, Wan, S
core   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Internal networks revisited: Telepathy meets technology [PDF]

open access: yes, 2003
This conference paper is available to download from the publisher’s website at the link below.This is speculative paper that explores the paradigm-shifting concept of initiating a mind/body to computer communication or interaction, it is not intended ...
Baker, C
core  

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

The Digital Therapeutic Alliance and Human-Computer Interaction

open access: yesJMIR Mental Health, 2020
The therapeutic alliance (TA), the relationship that develops between a therapist and a client/patient, is a critical factor in the outcome of psychological therapy.
Simon D’Alfonso   +3 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Intelligent Human-Computer Interaction Based on Surface EMG Gesture Recognition

open access: yesIEEE Access, 2019
Urban intelligence is an emerging concept which guides a series of infrastructure developments in modern smart cities. Human–computer interaction (HCI) is the interface between residents and the smart cities, it plays a key role in bridging the gap in ...
Jinxian Qi   +4 more
semanticscholar   +1 more source

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