Results 61 to 70 of about 14,818,924 (232)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Novel pathways to value nature: how guided forest bathing promotes new relationships with nature

Ecology and Society
Our relationship with nature adapts to our daily nature routines and it is rarely challenged. Forest bathing has been studied for its well-being benefits, but its potential as a novel nature-based activity to enrich human-nature relationships has not yet
Matteo Giusti, Annelie I Vårhammar, Vanessa A Masterson, Petra Ellora Cau Wetterholm   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

THE FAMILY AND HUMAN ECOLOGY: HAVING REGARD FOR THE NATURE OF FAMILIAL RELATIONSHIPS

Forum Teologiczne, 2020
The idea of a “human ecology” is gaining ever more significance in the human sciences, where it indicates an interdisciplinary approach to the relation between human beings and their environment.
Stephan Kampowski
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Health and Human Relationships Consultative Committee (HHRCC)

, 2022
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Blackwood, Margaret
core  

Hydropower resettlement reshapes human–nature relationships: Insights from Southwestern China

People and Nature
Understanding how hydropower migrants perceive nature's contributions to people (NCP) and how these perceptions relate to their subjective well‐being (SWB) is essential for informing resettlement policies that promote a good quality of life.
Xiaoyin He, Wenjuan Zhao, Ronghua Zhong, Ranhao Sun   +3 more
doaj   +1 more source

Exploring human-nature relationships in academic literature on the nitrogen cycle

Ecosystems and People
The nitrogen (N) cycle is a familiar concept. As is the much simplified, often diagrammatic, representation commonly used to illustrate the scale, importance and interconnectedness of this global cycle that links air, water, rocks and living beings ...
Bede West, Maximilian Bauer, Charis Chalkiadakis, Nicolas Dendoncker, Tanya M. González-Martínez, André Mascarenhas, Francesca Leucci, Benjamin B. Phillips, Konstantina Tania Ploumi, Carolina Rodriguez, Marie Vandewalle, Carla-Leanne Washbourne   +11 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source