Results 111 to 120 of about 1,764,727 (264)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Structure-Interaction Theory: Conceptual, Contextual and Strategic Influences on Human Communication

Russian journal of linguistics: Vestnik RUDN, 2015
This paper addresses Structure-Interaction Theory (SIT), a theoretical framework that both describes communication messages as well as assists in making predictions about how human communication can be improved based on listener preferences for message ...
Steven A Beebe
doaj  

Modelling Human-Structure Interaction in Pedestrian Bridges Using a Three-Dimensional Biomechanical Approach

Applied Sciences
Pedestrian bridges, which are essential in urban and rural infrastructures, are vulnerable to vibrations induced by pedestrian traffic owing to their low mass, stiffness, and damping.
Juan D. Aux, Bryan Castillo, Johannio Marulanda, Peter Thomson   +3 more
doaj   +1 more source

Human-data interaction

, 2016
We have moved from a world where computing is siloed and specialised, to a world where computing is ubiquitous and everyday. In many, if not most, parts of the world, networked computing is now mundane as both foreground (e.g., smartphones, tablets) and ...
Crabtree, Andy, Mortier, Richard, Crowcroft, Jon, Henderson, Tristan, McAuley, Derek, Haddadi, Hamed   +5 more
core  

DroEye : introducing a social eye prototype for drones

, 2020
A drone agent can benefit from exhibiting social cues, as introducing behavioral cues in robotic agents can enhance interaction trust and comfort with users.
Mohammad Obaid, Scott Andrew Brown, Mubin, Omar (R17188), Yantac, Asım E., Kuzuoka, Hideaki, Hideaki Kuzuoka, Obaid, Mohammad, Otsuki, Mai, Asim Evren Yantac, Omar Mubin, Brown, Scott A., Mai Otsuki   +11 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Handbook of human-computer interaction

, 1997
This completely revised edition, of the Handbook of Human-Computer Interaction, of which 80% of the content is new, reflects the developments in the field since the publication of the first edition in 1988.
Landauer, Thomas K., Prabhu, Prasad V, Landauer, Thomas K, Prabhu, Prasad V., Helander, Martin   +4 more
core  

Effects of eye contact and iconic gestures on message retention in human-robot interaction

, 2013
The effects of iconic gestures and eye contact on message retention in human-robot interaction were investigated in a series of experiments. A humanoid robot gave short verbal messages to participants, accompanied either by iconic gestures or no gestures
Dijk, van, E.T., Cuijpers, R.H., Torta, E., Torta, E.; id_orcid, Cuijpers, R.H.; id_orcid   +4 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Habituated interaction and social objects

, 2013
In this position paper we draw from critical approaches to the concept of habit from cultural theory to argue that considering the sociality of everyday objects might be productive for understanding and designing for habituated interaction within the ...
Brereton, Margot, Robertson, T, Nansen, B, Durick, JI, Robertson, Toni, Brereton, M, Durick, J, Vetere, Frank, Vetere, F, Nansen, Bjorn, Durick, Jeannette   +10 more
core