Results 151 to 160 of about 1,764,727 (264)

Sequence and structural alignments reveal insights into ANKLE2 evolution and function. [PDF]

Protein Sci
Fishburn AT, Florio CJ, Skawinski CLS, Becker SS, Holleman E, Robertson AE, Sitchon R, Chédin F, Shah PS.   +8 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

U1 snRNP and RNA polymerase II interaction is predominantly mediated by Prp40 rather than U1-70K in yeast. [PDF]

Nucleic Acids Res
Li X, Li J, Shi S, Kuang Z, Srivastava P, Issaian A, Bevers S, Wagley ME, D'Alessandro A, Zhao R.   +9 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A pore is a pore is a pore (or a hub?): VDAC oligomerization in mitochondrial connectivity and modulation. [PDF]

Biochem Soc Trans
De Pinto V, Battiato G, Conti-Nibali S, Cubisino SAM.   +3 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

HVIface: sequence-based deep learning for decoding human-virus protein-protein interfaces. [PDF]

Front Bioinform
Gupta KK, Vijayvargiya M, Paul G, Philip NS, Chauhan R.   +4 more
europepmc   +1 more source

Human-Swarm Interaction through Distributed Cooperative Gesture Recognition

The video presents the first results of a Swiss-funded project focusing on symbiotic peer-to-peer interaction and cooperation between humans and robot swarms.
Giusti, A., Gambardella, L. M., Bonardi, S., Nagi, J., Di Caro, G. A.   +4 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab-binding domain. [PDF]

Protein Sci
Nielipińska D, Orlikowska M, Nielipiński M, Sekuła B, Błażewska KM, Gendaszewska-Darmach E, Pietrzyk-Brzezińska AJ.   +6 more
europepmc   +1 more source