Results 191 to 200 of about 3,603,331 (295)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Structural potential of the 5' noncoding regions of the mRNAs encoding p53 isoforms. [PDF]

Acta Biochim Pol
Dutkiewicz M, Zydowicz-Machtel P.
europepmc   +1 more source

Investigation of Human-Structure Interaction Through Experimental and Analytical Studies

, 2012
Nicholas C. Noss
openalex   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The Binding of 3-O-Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation. [PDF]

Chembiochem
Troisi R, Rullo R, Napolitano V, Popowicz GM, De Vendittis E, Sica F.   +5 more
europepmc   +1 more source

Modeling Human-Structure Interaction Using a Controller System

, 2020
Albert R. Ortíz
openalex   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Mechanisms of APOBEC3 Packaging into HIV-1. [PDF]

Viruses
Nzivo M, Gertzen CGW, Luedde T, Gohlke H, Münk C.   +4 more
europepmc   +1 more source

A Structure Informed Atlas of Pan-Viral Interactions Reveals Features of Human Infection

, 2019
Gorka Lasso, Sandra V. Mayer, E. Winkelmann, Tim Chu, Oliver Elliot, Juan Ángel Patin͂o-Galindo, Kernyu Park, Raúl Rabadán, Barry Honig, Sagi Shapira   +9 more
openalex   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source