Results 41 to 50 of about 8,619,220 (248)

The human-wildlife conflict in Musk Deer National Park, Neelum Gureze Valley, Azad Jammu & Kashmir, Pakistan.

open access: yesBrazilian Journal of Biology, 2022
Growing human population is a solemn risk to biodiversity at a global level. Massive anthropogenic pressure and invasion in the natural habitats initiated the human-wildlife conflict in rural areas.
L. A. Khan   +9 more
doaj   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

open access: yesAdvanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li   +6 more
wiley   +1 more source

Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles

open access: yesAdvanced Science, EarlyView.
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller   +25 more
wiley   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

open access: yesAdvanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin   +9 more
wiley   +1 more source

Revealing stakeholders' motivation and influence in crane conservation in the Republic of Korea: Net‐Map as a tool

open access: yesConservation Science and Practice, 2021
Biodiversity conservation in protected areas requires strict legal limitations to land use. In the Civilian Control Zone (CCZ) of the Republic of Korea (ROK), military control has created an accidental sanctuary for the world's rarest crane species: the ...
Hyeyeon Sarah Jin   +6 more
doaj   +1 more source

Complex Human-Shark Conflicts Confound Conservation Action

open access: yesFrontiers in Conservation Science, 2021
Human-wildlife conflicts are a growing phenomenon globally as human populations expand and wildlife interactions become more commonplace. While these conflicts have been well-defined in terrestrial systems, marine forms are less well-understood.
Colin A. Simpfendorfer   +2 more
doaj   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

open access: yesAdvanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu   +27 more
wiley   +1 more source

Human-wildlife conflict and community perceptions towards wildlife conservation in and around a biodiverse National Park, northern Ethiopia

open access: yesGlobal Ecology and Conservation
Crop raiding and livestock predation significantly influence the perception of the local community regarding wildlife conservation. The primary aim of this study was to evaluate the scope, characteristics and origin of human-wildlife conflict, as well as
Esayas Embaye Kidane   +3 more
doaj   +1 more source

Understanding people's willingness to implement measures to manage human-bear conflict in Florida [PDF]

open access: yes, 2014
Moderator: Stewart Breck.Presented at the 8th international congress for wildlife and livelihoods on private and communal lands: livestock, tourism, and spirit, that was held on September 7-12, 2014 in Estes Park, Colorado.Video presenter: Elizabeth ...
Telesco, David, speaker   +4 more
core   +1 more source

Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures

open access: yesAdvanced Science, EarlyView.
ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels   +12 more
wiley   +1 more source

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