Results 111 to 120 of about 167,815 (294)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Love Whose Name Cannot be Spoken: Queering the Human-Animal Bond [PDF]

open access: yes, 2010
The hermeneutic category of queer has established itself as a powerful tool of social criticism and political action. Questioning and crossing identitarian barriers, and drawing attention to the ways to which non-normative identities are repressed by ...
DELL'AVERSANO, CARMEN
core  

Effects of adding different levels of fructooligosaccharide to diet on productive performance, egg quality traits, immune response and blood metabolites in commercial laying hens

open access: yesVeterinary Medicine and Science
Background A prebiotic is defined as an indigestible feed substance that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the large intestine, thereby improving host health and ...
Salah Mahdi Alsherify, Ahmad Hassanabadi
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Women and Animals in Affiliative Relationship: Healing Characteristics of the Animal Human Bond [PDF]

open access: yes, 2010
Gender is a basic organizing principle that profoundly shapes material conditions of women\u27s lives. Ecofeminism posits an association and joint oppression among women, animals, and nature, while feminist methodologies expose previously hidden aspects ...
Feeney, Pamela
core  

Understanding and accessing the continuum of human/animal support services: A scoping review

open access: yesHuman-Animal Interactions
Background: Approximately 66% of US households have companion animals (CAs); the majority view them as family (American Pet Products Association, 2023–2024).
Lisa Townsend   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Friend in Prison: Human-Animal Bond, Stress and Self-Esteem of Detained Juveniles in Dutch Cell Dogs. [PDF]

open access: yesAnimals (Basel), 2022
Karkdijk EM   +4 more
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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