Results 91 to 100 of about 167,815 (294)

A Global Survey of the Views of Practicing Companion Animal Veterinarians on Their Undergraduate Curriculum and Their Access to Continuing Education Resources [PDF]

open access: yes, 2023
A global survey was developed to gain insight into the opinion of companion animal veterinarians about their undergraduate education and their access to continuing education on the following topics: client communication, animal welfare, surgical ...
van Lith, Hein A., Endenburg, Nienke
core  

Epidemiology of cat bites to people in Uruguay: Effects of the age and sex of the victim, season of the year and the COVID-19 pandemic

open access: yesOpen Veterinary Journal
Background: Cat bites to people are an important public health problem. However, very little information exists on the epidemiology of people bitten by cats at the level of an entire country in Latin America.
Juan Pablo Damian   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

One Health zooeyia in our asocial age: A transdisciplinary and systems approach to the human-animal bond

open access: yesCABI One Health
Background: Companion animals can play vital roles in promoting human health and well-being, with the potential to mitigate contemporary social concerns about human isolation and loneliness. Zooeyia, recognized as the positive inverse of ‘zoonosis’, is a
Colleen Anne Dell   +6 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Development of Educational Fact Sheets on Nutrition, Enrichment, and Assistance Animals to Enhance the Human Animal Bond [PDF]

open access: yes, 2023
As of 2022, 90.5 million US families own a pet, but nearly 8 million animals are surrendered to shelters yearly despite this growing number of pet owners. This project aims to create science-based fact sheets to increase the bond between people and their
Rindels, Jordan
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Animal-assisted pedagogy : human-animal bond, developmental benefits and practical considerations [PDF]

open access: yes, 2021
In recent years, animal-assisted pedagogy (AAP) has gained more attention both in the media and in the educational field. Some schools and libraries have seemed to include animals as a common support in the learning process.
Jääskö, Iida   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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