Results 71 to 80 of about 9,912,829 (282)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The biology of the human–animal bond

open access: yesAnimal Frontiers, 2014
Our relationship with domestic animals is rooted in evolutionary, psychological, and physiological processes. There are significant health benefits for people associated with their interaction with animals. There are significant health benefits for animals associated with their interaction with people. Animals can be effectively utilized in therapeutic
openaire   +1 more source

Evaluation of owners’ attitudes towards veterinarian attire in the small animal specialty setting in North America

open access: yesVeterinary Medicine and Science, 2019
Previous studies in human medicine have found that patients prefer their doctors to be more formally attired, and that this influences their trust and confidence in their physician.
Kathryn A. Robb   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

A Bright Future for Human-Animal Interaction Research

open access: yesHuman-Animal Interactions, 2023
Steven Feldman
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

The human-animal bond's role with the abused child [PDF]

open access: yes, 1997
The purpose of this study was to investigate adults who were abused as children and the mediative impact of human and animal supportive relationships on the self-esteem, nurturant behavior, and anger/aggression of the abused child as both a child and an ...
Nebbe, Linda
core   +1 more source

Canine emotions and the bond between humans and dogs

open access: yesAnimal Sentience, 2017
I explore how the findings reviewed by Kujala (2017) influence our understanding of the human-dog bond. The special social cognitive abilities of dogs may be unique among animal species, probably influenced by the circumstances surrounding canine ...
Robert G. Franklin
doaj   +1 more source

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