Results 51 to 60 of about 9,912,829 (282)

Relational Healing Through Animals: The Human-Animal Bond Therapist Toolkit

, 2021
Early attachment experiences and the resulting attachment security that develops has a lasting impact on human mental health and well-being, as well as challenges to interpersonal relationships.
Malone, Kate
core  

Parental status influences human-to-pet caregiving behaviors, attachment, and attitudes in a Finnish sample

Human-Animal Interactions, 2023
A growing body of literature suggests people are choosing to forego parenthood, bringing companion animals into the home as a focus for people’s attachment and caretaking behavior instead.
Shelly Volsche, Sydney Schultz, Sara Alsaifi, Marika Melamies, Jari Pulkkinen   +4 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Two Sides of the Non-Human-Animal Bond: Reflections on Using and Abusing Companion Animals

, 2022
This chapter concerns the complexity of interspecies relationships in contemporary world. These relationships are ever-changing, yet continuously prone to anthropocentric attitudes and practices, prompting a reflection on the ways people use and abuse ...
Karin Hediger, Pręgowski, Michal, Enders-Slegers, Marié-Jose, Hediger, K.; id_orcid, Pregowski, Michal Piotr, Hediger, Karin, Michał Piotr Pręgowski, Marie-José Enders-Slegers, Enders - Slegers, M.J.   +8 more
core   +1 more source

Observation of human-animal interaction for research (OHAIRE) behavior coding in a randomized control trial of children with attention-deficit hyperactivity disorder (ADHD) and a canine-assisted intervention

Frontiers in Psychiatry
IntroductionDiagnosed in about 10% of children in the United States, attention-deficit hyperactivity disorder (ADHD) is characterized by symptoms including inattention, hyperactivity, and impulsivity.
Leanne O. Nieforth, Noémie A. Guerin, Annamarie Stehli, Sabrina E. B. Schuck, Katherine Yi, Marguerite E. O’Haire   +5 more
doaj   +1 more source

Dogs Supporting Human Health and Well-Being: A Biopsychosocial Approach

Frontiers in Veterinary Science, 2021
Humans have long realized that dogs can be helpful, in a number of ways, to achieving important goals. This is evident from our earliest interactions involving the shared goal of avoiding predators and acquiring food, to our more recent inclusion of dogs
Nancy R. Gee, Kerri E. Rodriguez, Aubrey H. Fine, Janet P. Trammell   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source