Results 41 to 50 of about 167,815 (294)
Frontiers in Veterinary Science, 2022 Dogs are relinquished to animal shelters for animal-related or guardian-related reasons. Understanding what drives relinquishment patterns is essential for informing intervention opportunities to keep animals with their guardians.
Bailey H. Eagan +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Relational Healing Through Animals: The Human-Animal Bond Therapist Toolkit [PDF]
, 2021 Early attachment experiences and the resulting attachment security that develops has a lasting impact on human mental health and well-being, as well as challenges to interpersonal relationships.
Malone, Kate
core
Human-Animal Interactions, 2023 A growing body of literature suggests people are choosing to forego parenthood, bringing companion animals into the home as a focus for people’s attachment and caretaking behavior instead.
Shelly Volsche +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Creature comforts: An exploration of pet owners and their experiences of wellbeing gained through their relationships with their companion animals [PDF]
, 2013 The aim of this phenomenological research was to gain greater understanding of people’s lived experience of their relationships with companion animals. Of particular interest were the everyday aspects of the relationship.
Johnson, Jennifer J.
core
Companion Animals as Buffer against the Impact of Stress on Affect: An Experience Sampling Study
Animals, 2021 Companion animals have been identified as a unique source of social support and as contributors to mental wellbeing. This study uses the Experience Sampling Method to test whether this effect is due to stress-buffering.
Mayke Janssens +6 more
doaj +1 more source