Results 81 to 90 of about 9,912,829 (282)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Australian animal painting and the human-animal bond in art

open access: yes, 2014
Animal painting is a critically important part of Australian art history, yet it has been afforded scant–if any–scholarly attention. Additionally, as the genre reached an apotheosis in the nineteenth century, animal painting represents a window into ...
Kovacic, Katherine Vanessa
core   +1 more source

ANIMAL WELFARE AND THE HUMAN-ANIMAL BOND IN STUDENT EDUCATION – HOW CAN WE UNDERSTAND ANIMAL FEELINGS? HOW DO WE ASK FOR CONSENT FROM A HORSE?

open access: yesSlovenian Veterinary Research
Students in veterinary education want positive interactions with their clients, but learn that a stressed animal can become unpredictable. If students can learn how to measure or evaluate the animal’s affective state before the physical exam, they can ...
Nichole Anderson
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Epidemiology of cat bites to people in Uruguay: Effects of the age and sex of the victim, season of the year and the COVID-19 pandemic

open access: yesOpen Veterinary Journal
Background: Cat bites to people are an important public health problem. However, very little information exists on the epidemiology of people bitten by cats at the level of an entire country in Latin America.
Juan Pablo Damian   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The role of attention, attitude, culture, and social expectancies in the human-animal bond : a biopsychosocial approach. [PDF]

open access: yes, 2010
The human-animal bond may positively impact human health. However, employing the human-animal bond in human health and behavioral treatments strategies faces several unresolved issues.
Shoemake, Elizabeth G.
core  

One Health zooeyia in our asocial age: A transdisciplinary and systems approach to the human-animal bond

open access: yesCABI One Health
Background: Companion animals can play vital roles in promoting human health and well-being, with the potential to mitigate contemporary social concerns about human isolation and loneliness. Zooeyia, recognized as the positive inverse of ‘zoonosis’, is a
Colleen Anne Dell   +6 more
doaj   +1 more source

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