Results 41 to 50 of about 847,925 (260)

Shaping towns through time: geology and urbanization in the historical context of Woldia, Ethiopia

Frontiers in Environmental Archaeology
The study explores the relationships between geological formations, socio-political dynamics, and urbanization processes in Woldia Township, Ethiopia, focusing on their impact on urban development and environmental sustainability through a historical ...
Fentaw Baye
doaj   +1 more source

Human-built environment interactions: the relationship between subjective well-being and perceived neighborhood environment characteristics

Scientific Reports, 2022
The neighborhood is one of the most fundamental urban elements and acts as the intermediary link between the city and citizens to enhance the quality of life.
Ali Reza Sadeghi, Maryam Ebadi, Fatemeh Shams, Sina Jangjoo   +3 more
doaj   +1 more source

Climate, vegetation, and weathering across space and time in Lake Tanganyika (tropical eastern Africa)

Quaternary Science Advances, 2021
Climate and vegetation influence weathering rates and processes; however, evaluating the effects of each and feedbacks between systems, has yet to be accomplished for many types of landscapes.
Sarah J. Ivory, Michael M. McGlue, Cara Peterman, Patrick Baldwin, Joseph Lucas, Andrew Cohen, James Russell, Justina Saroni, Emma Msaky, Ishmael Kimirei, Michael Soreghan   +10 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Editorial for the Special Issue: “Human-Environment Interactions Research Using Remote Sensing”

Remote Sensing, 2022
In the wake of increasingly frequent extreme weather events and population growth in hazard-prone areas worldwide, human communities are faced with growing threats from natural hazards [...]
Nina S.-N. Lam, Heng Cai, Lei Zou
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Reconsidering the role of the built environment in human–wildlife interactions

People and Nature, 2021
In facing our greatest challenges, researchers have questioned where the ‘wild things’ will reside in the future, and large carnivores have been a primary focal area.
Christopher Serenari
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

ENVIRONMENT IN THE HUMAN PERCEPTION: GEOGRAPHICAL ASPECTS

Geography, Environment, Sustainability, 2011
The present work highlights the different aspects of human perception of environment, specific characteristics of the subjective estimation of its state and attitudes to environmental quality.
Diana Dushkova, Sebastian Lentz, Monika Micheel, Alexander Evseev, Boris Kochurov   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source