Results 101 to 110 of about 151,005,169 (300)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

MSPEECH (multiple sclerosis monitoring through speech interaction in clinic and at home): a Living Lab study protocol for co-created, speech-based digital biomarkers in multiple sclerosis

open access: yesFrontiers in Digital Health
Multiple sclerosis (MS) has heterogeneous trajectories and fluctuating symptoms that are often not captured by intermittent clinic assessments. Digital health tools can provide frequent, low-burden measurements, but clinical translation requires ...
Tina Lemkau   +12 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Sophie Doulut, The Land of the Rings

open access: yes
That day, as we were standing at the Galway Fort of the Ring,You folded your knee and offered me a handmade shiny ring,Not Queen Isolde’s emerald and antique gold token ring,That King Mark had twisted round her ring finger -Not THAT ring, Nor even ...
The LOOP team
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Demo 06-09 Loop the Loop

open access: yes, 2001
A ball is rolled down an incline, as shown in Figure 1, performing a loop the loop at the bottom. For the ball to remain in contact with the incline at all times it must start at a height that will give it sufficient velocity at the top of the loop ...

core  

Sophie Doulut, The Epiphany of the Four Seasons coat

open access: yes
Proud forehead and burning glance, The Medicine Woman started her dance Chanting her prayers in a strange language Blurting spasmodic onomatopoeia from her lineage.
The LOOP team
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sophie Doulut, "From the Barbican to the Colony"

open access: yes
On English Plymouth harbour, there’s a gateway, The sky is framed within an invisible door Seagulls flitter through it and away, The way the Pilgrim Fathers walked through it before. A few yards away, the list of passengers reads On the stone walls of
The LOOP team
core   +1 more source

Social exclusion in virtual reality: touch modulates physiological markers of self-regulation

open access: yesHeliyon
A gentle caress activates C-Tactile (CT) afferents that project to social brain hubs, signalling social presence and buffering negative emotional states. We implemented a Cyberball paradigm to expose participants to social exclusion in virtual reality to
Letizia Della Longa   +6 more
doaj   +1 more source

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