Results 131 to 140 of about 109,968,647 (310)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Measurements in the Yucatan-Campeche Area in Support of the Loop Current Dynamics Study [PDF]

, 2014
A report detailing the measurements in the Yucatan-Campeche area in support of the Loop Current Dynamics ...
Ochoa, Jose, Candela, Julio, Romero, Angelica, Athie, Gabriela, Sheinbaum, Julio   +4 more
core  

"Meaningful Human Control in Artificial Intelligence": Practical Dilemmas of the Consensus Principle in Artificial Intelligence

Yixue yu zhexue
The concept of "meaningful human control in artificial intelligence" has been proposed in the context of artificial intelligence (AI) development, emphasizing human oversight over AI systems' autonomous decision-making.
Lin ZOU, Yonghui MA
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

A Nonlinear Modeling Framework for Force Estimation in Human-Robot Interaction

IEEE Access
In modern applied research concerning human-machine interaction, the possibility of increasing the degree of intelligence and dexterity of the controlled plant by imitating human control dynamics has been a primary objective.
Adriano Scibilia, Nicola Pedrocchi, Luigi Fortuna   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Modelling Human Decision-making based on Aggregate Observation Data

, 2017
Being able to infer the goals, preferences and limitations of humans is of key importance in designing interactive systems. Reinforcement learning (RL) models are a promising direction of research, as they are able to model how the behavioural patterns ...
Kangasrääsiö, Antti, Kaski, Samuel
core  

Enacting Proprioceptive Predictions in the Rubber Hand Illusion

Frontiers in Human Neuroscience, 2022
Jakub Limanowski, Jakub Limanowski
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

From Precision to Perception : User Surveys in the Evaluation of Keyword Extraction Algorithms

Stricter regulations on personal data are causing a shift towards contextual advertising, where keywords are used to predict the topical congruence between ads and their surrounding media contexts - an alignment shown to enhance advertising effectiveness.
Björklund, Johanna, Leckner, Sara, Cai, Jingwen   +2 more
core   +1 more source