Results 61 to 70 of about 156,269,237 (277)
A unified closed-loop stability measure for finite-precision digital controller realizations implemented in different representation schemes [PDF]
A computationally tractable unified finite word length closed-loop stability measure is derived which is applicable to fixed-point, floating-point and block- floating-point representation schemes.
Whidborne, James F. +7 more
core +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
REDUCING LOADING ON THE CONTRALATERAL LIMB USING HUMAN-IN-THE-LOOP OPTIMIZATION [PDF]
In most everyday activities, we head towards a specific goal by updating our choices for a more direct path. However, there are specific clinical tasks where taking the direct path is more challenging.
Senatore, Siena
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Reducing Personalization Time and Energy Cost While Walking Outdoors with a Portable Exosuit
Human‐in‐the‐loop optimization (HILO) has maximized the benefits of using wearable robots. Although all previous HILO studies have shown promising results, the majority have been validated in laboratory settings.
Kimoon Nam +7 more
doaj +1 more source
Exoskeletons offer promising solutions for enhancing human mobility; however, personalizing assistance parameters to optimize physiological outcomes remains challenging.
Arash Mohammadzadeh Gonabadi +2 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Loop is delighted and honoured to announce that poet and playwright Adam Wyeth, who lives and works in Dublin, is as of June 2024 a patron of Loop. We look forward to continuing our conversation with Adam, begun at the excellent 2024 SAES Congress at ...
The LOOP team
core +1 more source

