Results 121 to 130 of about 16,052,994 (303)

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Interaction-Shaping Robotics: Robots That Influence Interactions between Other Agents [PDF]

Work in Human–Robot Interaction (HRI) has investigated interactions between one human and one robot as well as human–robot group interactions. Yet the field lacks a clear definition and understanding of the influence a robot can exert on interactions ...
Leite, Iolanda, Sebo, Sarah,, Gillet, Sarah,, Leite, Iolanda,, Vázquez, Marynel, Vázquez, Marynel,, Andrist, Sean,, Gillet, Sarah, Andrist, Sean, Sebo, Sarah Strohkorb   +9 more
core   +1 more source

Understanding preferences for nature's contributions to people between and within social actors sheds insights for inclusive conservation

People and Nature
Despite calls for wider inclusion of diverse actors in conservation management, researchers tend to lump actors together into one group, potentially overlooking heterogeneity within the groups themselves—in turn, hampering inclusiveness.
Milena Gross, Tuyeni Heita Mwampamba, John Sanya, Jasmine Pearson, Jennifer Sesabo, Berta Martín‐López   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Modeling Human-Robot Interaction Based on Generic Interaction Patterns [PDF]

, 2010
Peltason J, Wrede B. Modeling Human-Robot Interaction Based on Generic Interaction Patterns. In: AAAI Fall Symposium: Dialog with Robots. Arlington, VA, USA: AAAI Press; 2010.While human-robot interaction is typically limited to restrictive command ...
Peltason, Julia, Wrede, Britta ; https://orcid.org/   +1 more
core  

DroEye : introducing a social eye prototype for drones

, 2020
A drone agent can benefit from exhibiting social cues, as introducing behavioral cues in robotic agents can enhance interaction trust and comfort with users.
Mohammad Obaid, Scott Andrew Brown, Mubin, Omar (R17188), Yantac, Asım E., Kuzuoka, Hideaki, Hideaki Kuzuoka, Obaid, Mohammad, Otsuki, Mai, Asim Evren Yantac, Omar Mubin, Brown, Scott A., Mai Otsuki   +11 more
core   +1 more source

Sociobiotechnical systems: a new approach to humanity-nature interaction

Sociologicheskaja nauka i social'naja praktika, 2016
The concept of socio-bio-technical system (SBT-system) as an interdisciplinary theoretical instrument for analysis of utmost complex geosphere processes is offered and substantiated. The existing dichotomy concepts like ‘society-nature’, ‘rural-urban’, ‘local-global’ are not fit to integrated, controversial, mobile and not linear processes that are ...
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source