Results 111 to 120 of about 31,267,735 (386)
Tydskrif vir Letterkunde, 2018 References to death and mortality play an (increasingly) important role in the works of Lettie Viljoen/Ingrid Winterbach. In this article the central role of personifications of death in her novels is investigated.
Thys Human
doaj
Alternatywizm, dysjunktywizm i pluralizm doświadczeniowy [PDF]
, 2018 The claim currently known as “disjunctivism” is usually interpreted in terms of exclusive disjunction. However, it can be also explicated through the lens of alternative denial.
Zięba, Paweł J.
core +2 more sources
Signatures of mutational processes in human cancer
Nature, 2013 All cancers are caused by somatic mutations; however, understanding of the biological processes generating these mutations is limited. The catalogue of somatic mutations from a cancer genome bears the signatures of the mutational processes that have been
L. Alexandrov +69 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
CAHRS hrSpectrum (November-December 2008) [PDF]
, 2008 HRSpec2008_12.pdf: 478 downloads, before Oct.
Center for Advanced Human Resources Studies
core +1 more source
WPŁYW MALARSTWA SURREALISTYCZNEGO NA REKLAMĘ WSPÓŁCZESNĄ [PDF]
, 2012 The purpose of this article is to examine the influence of surrealistic painting on contemporary advertising, taking into consideration the differences in use of surrealistic references on three levels of literalness: advertisement citing specific ...
Sonia Bednarska
core +1 more source
Oxidative Stress: Harms and Benefits for Human Health
Oxidative Medicine and Cellular Longevity, 2017 Oxidative stress is a phenomenon caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a biological system to detoxify these reactive products.
G. Pizzino +8 more
semanticscholar +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Psychobiology of Attachment and Trauma—Some General Remarks From a Clinical Perspective
Frontiers in Psychiatry, 2019 Attachment refers to a psychobiological principle that is deeply rooted in evolutionary development; it is thought to contribute a major advantage in the survival of the social group.
Theresa Lahousen +4 more
doaj +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source