Results 121 to 130 of about 12,297,553 (312)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Terms and Conditions of Administrative and Professional Staff Employment

open access: yes, 2011
Human ...
Office of the Vice President for Human Resources
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Human control in mineral processing plants: An operator centered investigation

open access: yes, 2010
Mineral processing plants present a complex and dynamic process control environment where human operation is widely regarded as the bottleneck of overall plant performance. This paper presents an initial field study to investigate factors and issues that
Powell, Malcolm   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The relationship between attachment, primary emotions and positive/negative spirituality: a path analysis

open access: yesFrontiers in Public Health
ObjectiveThe present study investigates what may influence individuals to experience their religiosity/spirituality as either subjectively positive [religious or spiritual (r/s) wellbeing] or as negative (r/s struggles).
Anton Freund   +9 more
doaj   +1 more source

Humans, Humanities, and Humanism in an Age of Technology [PDF]

open access: yes, 2016
Harry Potter’s world as described by J.K. Rowling in a series of books for children is not the world of us, ordinary humans.1 Owls delivering letters overnight would be handy. Howling letters that criticize their recipients in public might be embarrassing.
openaire   +2 more sources

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Anxious and depressive symptoms mediate the influence of sleep quality on suicidality in young adults

open access: yesFrontiers in Public Health
This study investigated how sleep quality affects the global severity of psychiatric symptoms, including suicidality, in young adults. Poor sleep quality has a significant impact on mental health and should therefore be given special attention in ...
Corinna Slanitz   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy