Results 121 to 130 of about 31,267,735 (386)

China and the Humanities: At the Crossroads of the Human and the Humane [PDF]

open access: yes, 2013
This contains the sections of this volume produced by the editor, including the front matter, Preface, Introduction and Index.
openaire   +2 more sources

The Role of Attachment in Poly-Drug Use Disorder: An Overview of the Literature, Recent Findings and Clinical Implications

open access: yesFrontiers in Psychiatry, 2019
Background: Substance use disorders (SUDs) represent a worldwide epidemic with extensive costs to the individual and to society. Occasionally described as an attachment disorder, they have been linked to various impairments in self-regulation and social ...
Michaela Hiebler-Ragger   +4 more
doaj   +1 more source

Molecular determinants of acute kidney injury [PDF]

open access: yes, 2015
BACKGROUND: Acute kidney injury (AKI) is a condition that leads to a rapid deterioration of renal function associated with impairment to maintain electrolyte and acid balance, and, if left untreated, ultimately irreversible kidney damage and renal ...
Human, Christin, Husi, Holger
core   +2 more sources

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

An ideal for leadership - Psalm 72: The (wise) king - Royal mediation of God�s universal reign

open access: yesVerbum et Ecclesia, 2002
Psalm 72 propounds illuminating theological perspectives on leadership. The central figure in the psalm is the king. Throughout the Ancient Near East the king played a distinctive role, not only in contemporary politics, but also in religious life ...
D. J. Human
doaj   +1 more source

Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability [PDF]

open access: yes, 2018
R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may occur transiently during transcription, playing essential biological functions. However, persistent R loops may become pathological
Aguilera López, Andrés   +2 more
core   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Humans [PDF]

open access: yesCurrent Biology, 2004
Hughes, David A   +2 more
openaire   +3 more sources

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