Results 161 to 170 of about 31,267,735 (386)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

War and peace: the ANZAC spirit and human rights [PDF]

open access: yes
A series of papers given by the various speakers at the Australian Human Rights Commission’s War and Peace: The Anzac spirit and human rights 2014 seminar. Summary Every year around Anzac Day, Australians and New Zealanders remember those who fought in
Australian Human Rights Commission
core  

Customers Suffer From Employee Churn: High Turnover Makes It Harder to Provide Top Service [PDF]

open access: yes, 2009
Key Findings: • As rates of voluntary turnover climb within key business units, customers are more likely to report bad customer service. • When new workers arrive, established workers have to take time away from customer service to train the
Center for Advanced Human Resource Studies, ILR School, Cornell University.
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Harness the Power of Frontline Supervisors to Turn HR Policies into Performance Gains [PDF]

open access: yes, 2010
Key Findings: • Frontline supervisors play a critical role in implementing HR policies by developing employees and managing performance. • Coaching counts—one-on-one feedback from frontline supervisors increases the bottom-line by improving ...
Center for Advanced Human Resource Studies, ILR School, Cornell University
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Beyond Tenure: Building Managerial Competencies through Developmental Assignments [PDF]

open access: yes, 2009
Key Findings: • The developmental quality of job assignments is critical for building managerial competencies. What matters most isn’t how long junior managers have been in an assignment, but the nature of that assignment. • Not all junior
Center for Advanced Human Resource Studies, ILR School, Cornell University
core   +1 more source

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