Results 81 to 90 of about 23,986,359 (358)

Human-Centered Humanities

open access: yesDigital Humanities in the Nordic and Baltic Countries Publications, 2020
This pilot study proposes the use of so-called stimulus material during interviews for requirements elicitation as part of the design process of a digital archive. Designing complex systems like digital archives is not straightforward as users of these systems have specific needs and tasks that designers need to be aware of before the implementation ...
Tamás Fergencs   +3 more
openaire   +1 more source

Eurospective Fall 2009: conversations with European artists and writers [PDF]

open access: yes, 2009
This is the archive of the promotional flyer for the IHS project "Eurospective Fall 2009: conversations with European artists and ...
Boston University Institute for Human Sciences
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

All Turnover Is Not Created Equal: Gaining Insight Into How Employee Departures Affect Organizational Units [PDF]

open access: yes, 2012
[Excerpt] Key Findings: Traditional turnover ratios–the number of employees leaving versus the total number in a unit—may not accurately describe how employee departures affect business unit performance.
Center for Advanced Human Resource Studies
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Getting to Know You: Self-awareness Is Key for High-Performing, Adaptive Teams [PDF]

open access: yes, 2010
KEY FINDINGS · Role identification behaviors, or information exchanges among team members regarding individuals’ roles within a team, are crucial to the development of a team’s self awareness.
Center for Advanced Human Resource Studies
core   +1 more source

EXPLAINING THE EUROPEAN COMMUNITY - AUSTRALIA WINE TRADE AGREEMENT. IMPACT OF NATIONAL PREFERENCES ON A CHANGE OF SCENE IN TRADE POLITICS [PDF]

open access: yes, 2012
In January 1994, the European Community and Australia signed the Agreement on Trade in Wine. Considering the dramatic changes in the international wine market, this strategy of policy coordination is hardly surprising.
Mariusz Rybak
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

CAHRS hrSpectrum (January - February 2008) [PDF]

open access: yes, 2008
HRSpec2008_02.pdf: 111 downloads, before Oct.
Center for Advanced Human Resource Studies
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy