Results 21 to 30 of about 222,876 (256)
Human adenoviruses (HAdV) express either one or two virus-associated RNAs (VA RNAI or VA RNAII). The structure of VA RNA resembles human precursor microRNAs (pre-miRNA), and, like human pre-miRNA, VA RNA can be processed by DICER into small RNAs that ...
Eric R. McIndoo +3 more
doaj +1 more source
Background Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4+ T cells has been reported to be associated with sustained protection from ...
Maarten L. Zandvliet +12 more
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Human adenovirus associated with severe cold agglutinin syndrome: a rare complication in Pediatrics [PDF]
Objective: The objectives of this study were to describe the first pediatric case of cold agglutinin syndrome (CAS) triggered by human adenovirus and review the literature.
Julia Loureiro Sion +3 more
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Brain tumors induced in rats by human adenovirus type 12 [PDF]
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Matsuo, Keisuke +5 more
core +1 more source
A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus
Elucidation of the interplay between viruses and host cells is crucial for taming viruses to benefit human health. Cancer therapy using adenovirus, called oncolytic virotherapy, is a promising treatment option but is not robust in all patients.
Enkhjin Saruuldalai +16 more
doaj +1 more source
A New Bovine Adenovirus Related to Human Adenovirus.
SummaryA second bovine adenovirus has been isolated. The virus is antigenically similar to a human virus as determined by 1) neutralization with human gamma globulin and human adult sera, and 2) possession of a complement fixing antigen similar to that of the human adenovirus. The related type of human adenovirus remains unknown.
M, KLEIN, J, ZELLAT, T C, MICHAELSON
openaire +2 more sources
Immunological Study of Reconstructed Common Ancestral Sequence of Adenovirus Hexon Protein
Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existing ...
Yingchen Wang +12 more
doaj +1 more source
Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]
<p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo +47 more
core +2 more sources
Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway [PDF]
Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional design
Curiel, David T. +5 more
core +2 more sources
Evolution and diversity of human adenoviruses isolated from patients with keratoconjunctivitis
Background and Objectives: Human adenovirus type 8 is a highly contagious eye disease and is considered as the most common epidemic keratoconjunctivitis worldwide.
Chiman Karami +7 more
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